Plasmodium falciparum-Infected Erythrocytes Induce Granzyme B by NK Cells through Expression of Host-Hsp70

E Böttger, G Multhoff, JFJ Kun, M Esen - PLoS One, 2012 - journals.plos.org
In the early immune response to Plasmodium falciparum-infected erythrocytes (iRBC),
Natural Killer (NK) cells are activated, which suggests an important role in innate anti …

NK cells inhibit Plasmodium falciparum growth in red blood cells via antibody-dependent cellular cytotoxicity

G Arora, GT Hart, J Manzella-Lapeira… - Elife, 2018 - elifesciences.org
Antibodies acquired naturally through repeated exposure to Plasmodium falciparum are
essential in the control of blood-stage malaria. Antibody-dependent functions may include …

Heterogeneous human NK cell responses to Plasmodium falciparum-infected erythrocytes

DS Korbel, KC Newman, CR Almeida… - The Journal of …, 2005 - journals.aai.org
Human NK cells can respond rapidly to Plasmodium falciparum-infected RBC (iRBC) to
produce IFN-γ. In this study, we have examined the heterogeneity of this response among …

Cytotoxicity of human natural killer (NK) cell subsets for Plasmodium falciparum erythrocytic schizonts: stimulation by cytokines and inhibition by neomycin

ASS Orago, CA Facer - Clinical & Experimental Immunology, 1991 - Wiley Online Library
Quantification of human peripheral blood NK subsets has been made in a group of Kenyan
adults and children with acute P. falciparum malaria. Results were compared with data …

Cross-talk between T cells and NK cells generates rapid effector responses to Plasmodium falciparum-infected erythrocytes

A Horowitz, KC Newman, JH Evans… - The Journal of …, 2010 - journals.aai.org
Rapid cell-mediated immune responses, characterized by production of proinflammatory
cytokines, such as IFN-γ, can inhibit intraerythrocytic replication of malaria parasites and …

Memory‐like IFN‐γ response by NK cells following malaria infection reveals the crucial role of T cells in NK cell activation by P. falciparum

MBB McCall, M Roestenberg, I Ploemen… - European journal of …, 2010 - Wiley Online Library
NK cells are rapid IFN‐γ responders to Plasmodium falciparum‐infected erythrocytes
(PfRBC) in vitro and are involved in controlling early parasitaemia in murine models, yet little …

Contributions of natural killer cells to the immune response against Plasmodium

KS Burrack, GT Hart, SE Hamilton - Malaria Journal, 2019 - Springer
Natural killer (NK) cells are important innate effector cells that are well described in their
ability to kill virally-infected cells and tumors. However, there is increasing appreciation for …

Adaptive NK cells in people exposed to Plasmodium falciparum correlate with protection from malaria

GT Hart, TM Tran, J Theorell, H Schlums… - Journal of Experimental …, 2019 - rupress.org
How antibodies naturally acquired during Plasmodium falciparum infection provide clinical
immunity to blood-stage malaria is unclear. We studied the function of natural killer (NK) …

[HTML][HTML] γδ T cells kill Plasmodium falciparum in a granzyme-and granulysin-dependent mechanism during the late blood stage

MA Hernández-Castañeda, K Happ… - The Journal of …, 2020 - journals.aai.org
Plasmodium spp., the causative agent of malaria, have a complex life cycle. The exponential
growth of the parasites during the blood stage is responsible for almost all malaria …

A Duffy Binding—Like Domain Is Involved in the NKp30-Mediated Recognition of Plasmodium falciparum—Parasitized Erythrocytes by Natural Killer Cells

E Mavoungou, J Held, L Mewono… - The Journal of …, 2007 - academic.oup.com
The recent demonstration that purified natural killer (NK) cells lyse Plasmodium falciparum–
parasitized red blood cells (Pf-pRBCs) suggests that innate immunity is important in malaria …