DNA nanostructures have been engineered into various delivery systems for anti-cancer
chemotherapy. However, these nanostructures are hindered in their therapeutic applications …

A bioinspired cocoon-like anticancer drug delivery system consisting of a
deoxyribonuclease (DNase)-degradable DNA nanoclew (NCl) embedded with an acid …

We developed a novel self-assembled DNA nanostructure for anticancer drug delivery. The
resulting nanostructure was able to specifically target cancer cells and release the loaded …

Recently, oligonucleotides have attracted substantial attention in the field of cancer therapy
due to their target specificity and ability to modulate various molecular pathways. However …

Herein, we construct a structure-switchable gemcitabine (Ge)-containing DNA nanogel that
can respond to the intracellular acidic environment, subsequently facilitating the chemodrug …

Nanogels made of biomolecules are one of the potential candidates as a nanocarrier for
drug delivery applications. The unique structural characteristics and excellent …

Antisense oligonucleotides can be employed as a potential approach to effectively treat
cancer. However, the inherent instability and inefficient systemic delivery methods for …

DNA hydrogels with unique sequence programmability on nucleic acid framework manifest
remarkable attributes, such as high payload capacities, biocompatibility and biosafety. The …

Conventional chemotherapeutic drugs are nonselective and harmful toward normal tissues,
causing severe side effects. Therefore, the development of chemotherapeutics that can …

DNA nanostructures largely rely on pairing DNA bases; thus, sequence designing is
required. Here, this study demonstrates a sequence‐independent strategy to fabricate DNA …