BACKGROUND Initially identified as suppressors of metastasis in various types of cancer,
kisspeptins are a family of neuropeptides that are key regulators of the mammalian …

Several studies provide strong evidence suggesting that in addition to central
kisspeptin/KISS1R signaling, the peripheral uterine-and placental-based kisspeptin/KISS1R …

Kisspeptin is a neuropeptide that was originally discovered in 1996 from a metastasis
tumour suppressor gene, KISS1 and was appropriately named metastin. More recently, the …

Background Expression of kisspeptin (protein) and Kiss1r (mRNA) was recently documented
in the mouse uterus on D4 of pregnancy (the day of embryo implantation) suggesting that …

Kisspeptin and its receptor are central to reproductive health acting as key regulators of the
reproductive endocrine axis in humans. Kisspeptin is most widely recognised as a regulator …

The hypothalamic-based kisspeptin-signaling system is a major positive regulator of the
neuroendocrine-reproductive axis in mammals. During the last decade, major advances …

Kisspeptin and its G protein-coupled receptor KISS1R play key roles in mammalian
reproduction due to their involvement in the onset of puberty and control of the hypothalamic …

Kisspeptins are a family of neuropeptides that are critical for the puberty initiation and female
fertility. Plasma or serum kisspeptin is mainly derived from the placenta during pregnancy …

Background Ectopic pregnancy is a life-threatening condition for which novel screening
tools that would enable early accurate diagnosis would improve clinical outcomes …

The invasion of extravillous trophoblasts into the uterine wall is of crucial importance for
placental and fetal development, and its dysregulation has been implicated in a wide …