Evidence for anti-inflammatory effects of adalimumab in treatment of patients with major depressive disorder: A pilot, randomized, controlled trial

F Abbasian, S Bagheri, K Moradi… - Clinical …, 2022 - journals.lww.com
Background Literature has suggested that major depressive disorder (MDD) is accompanied
by higher concentrations of inflammatory biomarkers, which could sabotage response to …

Evaluation of inflammatory cytokines in drug-naïve major depressive disorder: a systematic review and meta-analysis

MR Islam, M Sohan, S Daria… - International …, 2023 - journals.sagepub.com
Objective: Altered levels of peripheral inflammatory and proinflammatory cytokine markers
affect the different clinical stages of major depressive disorder (MDD). A concrete …

Efficacy and acceptability of anti-inflammatory agents in major depressive disorder: a systematic review and meta-analysis

Y Du, Y Dou, M Wang, Y Wang, Y Yan, H Fan… - Frontiers in …, 2024 - frontiersin.org
Background Anti-inflammatory agents have emerged as a potential new therapy for major
depressive disorder (MDD). In this meta-analysis, our aim was to evaluate the …

Efficacy and safety of anti-inflammatory agents for the treatment of major depressive disorder: a systematic review and meta-analysis of randomised controlled trials

S Bai, W Guo, Y Feng, H Deng, G Li, H Nie… - Journal of Neurology …, 2020 - jnnp.bmj.com
Objectives To systematically review the efficacy and safety of anti-inflammatory agents for
patients with major depressive disorders. Methods We searched the literature to identify …

Inflammation and clinical response to treatment in depression: a meta-analysis

R Strawbridge, D Arnone, A Danese… - European …, 2015 - Elsevier
The depressive state has been characterised as one of elevated inflammation, which holds
promise for better understanding treatment-resistance in affective disorders as well as for …

Cool the Inflamed Brain: A Novel Anti-inflammatory Strategy for the Treatment of Major Depressive Disorder

WJ Su, T Hu, CL Jiang - Current Neuropharmacology, 2024 - ingentaconnect.com
Background: Abundant evidence suggests that inflammatory cytokines contribute to the
symptoms of major depressive disorder (MDD) by altering neurotransmission …

Clinical trials of anti-inflammatory treatments of major depression

N Müller - Inflammation and Immunity in Depression, 2018 - Elsevier
A mounting body of literature indicates a dysregulated immune system as the underlying
pathogenetic mechanism of major depression (MD), at least in a subgroup of patients …

Comparative efficacy and acceptability of anti-inflammatory agents on major depressive disorder: a network meta-analysis

X Hang, Y Zhang, J Li, Z Li, Y Zhang, X Ye… - Frontiers in …, 2021 - frontiersin.org
Background: With the growing importance of research about the association between
neuroinflammation and major depressive disorder (MDD), anti-inflammatory agents have …

A review of the relationship between proinflammatory cytokines and major depressive disorder

JJ Young, D Bruno, N Pomara - Journal of affective disorders, 2014 - Elsevier
Background Determining etiological factors and reviewing advances in diagnostic
modalities sensitive and specific to Major Depressive Disorder (MDD) is of importance in its …

Efficacy of anti‐inflammatory treatment on major depressive disorder or depressive symptoms: meta‐analysis of clinical trials

O Köhler‐Forsberg, C N. Lydholm… - Acta Psychiatrica …, 2019 - Wiley Online Library
Background No study has gathered evidence from all randomized clinical trials (RCT s) with
anti‐inflammatory drugs measuring antidepressant effects including a detailed assessment …