Recent studies have suggested a potential direct role of mild hyperuricemia in development
of chronic kidney disease independent of urate crystal formation. The present study was …

Hyperoxaluria is a condition where excessive oxalate is present in the urine. Many reports
have documented free radical generation followed by hyperoxaluria as a consequence of …

Hyperuricemia contributes to chronic kidney disease development. However, it has been
historically viewed with limited research interest. In this study, we mimicked the development …

Introduction Cystone is an approved Ayurvedic polyherbal proprietary medicine used in
India for various urinary disorders, including urolithiasis. Aim To evaluate the protective …

Background/Purpose: This research was performed to determine the effect of naringenin
(NAR) in experimental hyperuricemia (HU) induced by potassium oxonate (PO) on uric acid …

Background: Hyperuricemia (HU) is a metabolic disease characterized by high uric acid
levels in the blood. HU is a risk factor for diabetes, cardiovascular complications, metabolic …

To evaluate the role of the inducible nitric oxide synthase (iNOS), selective nuclear factor-kB
(NF-kB), and p38-mitogene-activated protein kinase (p38-MAPK) on hyperoxaluria-induced …

The interactions between the main cellular sources of ROS, such as mitochondria and
NADPH oxidase, are known to play an imperative role in the pathogenesis of hyperoxaluria …

Alterations of renal function during dietary-induced hyperuricemia in the rat. Hyperuricemia
was induced in rats ingesting a diet supplemented with 21/2% uric acid and 5% oxonic acid …

Hyperoxaluria and oxidative stress are risk factors in calcium oxalate (CaOx) stone
formation. Supplement with antioxidant could be effective in prevention of recurrent stone …