Inhibitory Potential of Mangiferin on Glucansucrase Producing Streptococcus mutans Biofilm in Dental Plaque

PM Emeka, LI Badger-Emeka, HIM Ibrahim… - Applied Sciences, 2020 - mdpi.com
Glucansucrase secreted by Streptococcus mutans and composed of virulence genes alters
oral microbiota, creating adherent environment for structural bacteria colony forming dental …

Sulfated vizantin inhibits biofilm maturation by Streptococcus mutans

M Oda, M Kurosawa, H Yamamoto… - Microbiology and …, 2020 - Wiley Online Library
Streptococcus mutans is the main pathogen of dental caries and adheres to the tooth
surface via soluble and insoluble glucans produced by the bacterial glucosyltransferase …

Inhibitory potential of EGCG on Streptococcus mutans biofilm: A new approach to prevent Cariogenesis

MIH Islam, S Arokiyaraj, M Kuralarasan, VS Kumar… - Microbial …, 2020 - Elsevier
Dental caries is a common cause for tooth loss and Streptococcus mutans is identified as the
etiologic pathogen. This study evaluates the inhibitory potential of Epigallocatechin gallate …

Raffinose inhibits Streptococcus mutans biofilm formation by targeting glucosyltransferase

SY Ham, HS Kim, E Cha, T Lim, Y Byun… - Microbiology …, 2022 - Am Soc Microbiol
Streptococcus mutans is a representative biofilm-forming bacterium that causes dental
caries through glucosyltransferase (GTF) activity. Glucans are synthesized from sucrose by …

Effect of Leuconustoc spp. on the formation of Streptococcus mutans biofilm

MS Kang, IC Kang, SM Kim, HC Lee… - Journal of …, 2007 - koreascience.kr
Insoluble glucans synthesized by Streptococcus mutans enhance the pathogenicity of oral
biofilm by promoting the adherence and accumulation of cariogenic bacteria on the surface …

Molecule targeting glucosyltransferase inhibits Streptococcus mutans biofilm formation and virulence

Z Ren, T Cui, J Zeng, L Chen, W Zhang… - Antimicrobial agents …, 2016 - Am Soc Microbiol
Dental plaque biofilms are responsible for numerous chronic oral infections and cause a
severe health burden. Many of these infections cannot be eliminated, as the bacteria in the …

Novel effect of plant lectins on the inhibition of Streptococcus mutans biofilm formation on saliva‐coated surface

B Islam, SN Khan, A Naeem, V Sharma… - Journal of Applied …, 2009 - academic.oup.com
Aims: Dental caries is caused by the disturbance in oral homeostasis, marked by a notable
increase in the population of Streptococcus mutans. Lectins are a group of plant proteins …

Application of chimeric glucanase comprising mutanase and dextranase for prevention of dental biofilm formation

R Otsuka, S Imai, T Murata, Y Nomura… - Microbiology and …, 2015 - Wiley Online Library
Water‐insoluble glucan (WIG) produced by mutans streptococci, an important cariogenic
pathogen, plays an important role in the formation of dental biofilm and adhesion of biofilm …

Hydroxychalcone inhibitors of Streptococcus mutans glucosyl transferases and biofilms as potential anticaries agents

B Nijampatnam, L Casals, R Zheng, H Wu… - Bioorganic & medicinal …, 2016 - Elsevier
Streptococcus mutans has been implicated as the major etiological agent in the initiation
and the development of dental caries due to its robust capacity to form tenacious biofilms …

Molecular mechanisms of inhibiting glucosyltransferases for biofilm formation in Streptococcus mutans

Q Zhang, Q Ma, Y Wang, H Wu, J Zou - International Journal of Oral …, 2021 - nature.com
Glucosyltransferases (Gtfs) play critical roles in the etiology and pathogenesis of
Streptococcus mutans (S. mutans)-mediated dental caries including early childhood caries …