The Vascular Endothelial-Cadherin Promoter Directs Endothelial-Specific Expression in Transgenic Mice

S Gory, M Vernet, M Laurent, E Dejana… - Blood, The Journal …, 1999 - ashpublications.org
Vascular endothelial-cadherin (VE-cadherin) is a calcium-dependent adhesive molecule,
exclusively and constitutively expressed in endothelial cells. Analysis of the VE-cadherin …

The human VE-cadherin promoter is subjected to organ-specific regulation and is activated in tumour angiogenesis

MH Prandini, I Dreher, S Bouillot, S Benkerri, T Moll… - Oncogene, 2005 - nature.com
Vascular endothelial (VE)-cadherin is exclusively expressed at interendothelial junctions of
normal and tumour vessels. In this report, we characterized the transcriptional activity of the …

Vascular endothelial (VE)-cadherin: only an intercellular glue?

E Dejana, G Bazzoni, MG Lampugnani - Experimental cell research, 1999 - Elsevier
Data collected during the past years indicate that AJ-and more specifically VE-cadherin play
an important role in endothelial cell biology. VE-cadherin may transfer information …

Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system

G Breier, F Breviario, L Caveda, R Berthier, H Schnurch… - 1996 - ashpublications.org
An early step in the formation of the extraembryonic and intraembryonic vasculature is
endothelial cell differentiation and organization in blood islands and vascular structures …

Targeted null-mutation in the vascular endothelial–cadherin gene impairs the organization of vascular-like structures in embryoid bodies

D Vittet, T Buchou, A Schweitzer… - Proceedings of the …, 1997 - National Acad Sciences
Vascular endothelial–cadherin (VE–cadherin) is exclusively expressed in endothelial cells
and is strictly located at cell-to-cell junctions. As the other members of the cadherin family …

High level of endothelial cell-specific gene expression by a combination of the 5′ flanking region and the 5′ half of the first intron of the VE-cadherin gene

H Hisatsune, K Matsumura, M Ogawa, A Uemura… - Blood, 2005 - ashpublications.org
To develop a tool to obtain a high level of gene expression specifically in endothelial cells
(ECs), we assessed enhancer activity of fragments in the first intron of the VE-cadherin gene …

Cardiac ischemia activates vascular endothelial cadherin promoter in both preexisting vascular cells and bone marrow cells involved in neovascularization

N Kogata, Y Arai, JT Pearson, K Hashimoto… - Circulation …, 2006 - Am Heart Assoc
Vascular endothelial cadherin (VE-cadherin) is expressed on vascular endothelial cells,
which are involved in developmental vessel formation. However, it remains elusive how VE …

Vascular endothelial–cadherin is an important determinant of microvascular integrity in vivo

M Corada, M Mariotti, G Thurston… - Proceedings of the …, 1999 - National Acad Sciences
In the present paper, we characterize an antibody, mAb BV13, directed to mouse vascular
endothelial (VE)-cadherin, a major adhesive protein of interendothelial adherens junctions …

Requirement of a GT box (Sp1 site) and two Ets binding sites for vascular endothelial cadherin gene transcription

S Gory, J Dalmon, MH Prandini, T Kortulewski… - Journal of Biological …, 1998 - ASBMB
Vascular endothelial cadherin (VE cadherin) gene encodes a Ca 2+-dependent cell
adhesion molecule required for the organization of interendothelial junctions. This gene is …

Genomic structure and chromosomal mapping of the mouse VE-cadherin gene (Cdh5)

P Huber, J Dalmon, J Engiles, F Breviario, S Gory… - Genomics, 1996 - Elsevier
Vascular endothelial cadherin (VE-cadherin) is located strictly at endothelial junctions and
appears to be a major adhesive component of cell to cell contacts. Genomic clones …