Historically, multiple sclerosis (MS) has been viewed as being primarily driven by T cells.
However, the effective use of anti-CD20 treatment now also reveals an important role for B …

Over the past two decades B cells have increasingly moved into the spotlight in multiple
sclerosis (MS) research. This interest was fuelled by growing understanding and acceptance …

Important antibody-independent pathogenic roles of B cells are emerging in autoimmune
diseases, including multiple sclerosis (MS). The contrasting results of different treatments …

There is ongoing debate on how B cells contribute to the pathogenesis of multiple sclerosis
(MS). The success of B‐cell targeting therapies in MS highlighted the role of B cells …

There is growing recognition that B cell contributions to normal immune responses extend
well beyond their potential to become antibody-producing cells, including roles at the innate …

B lymphocytes have essential roles in the autoimmune pathogenesis of multiple sclerosis
(MS). They regulate the autoimmune response and participate in the development of the …

Increasing evidence indicates the involvement of B cells in the pathogenesis of multiple
sclerosis (MS), but their precise roles are unclear. In this Review, we provide an overview of …

Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system
characterized by focal demyelination patches associated with inflammatory infiltrates …

Background: Collectively, research on the role of B-cells in the pathogenesis of multiple
sclerosis (MS) illustrates how translational medicine has given rise to promising therapeutic …

B cells, plasma cells and antibodies may play a key role in the pathogenesis of multiple
sclerosis (MS). This notion is supported by various immunological changes observed in MS …