N-methylinole-2-carboxylic acid Page 1 Al-Balqa' Journal, Vol. 6, No. 2 (1999) Elagbar
Synthesis of N-Substituted indoxyls and pharmacological screening of 3-acetoxyN-methylinole-2-carboxylic …

The esterification of 1-alkyl/aryl-3-ethoxy carbonyl-5-hydroxy-2-methyl indoles (1a-g) with
ethyl chloroacetate and ethyl chloroformate, afforded ethyl 5-(ethoxycarbonyl) methoxy]-1 …

Abstract A new series of 1, 5-disubstituted indole derivatives such as 5-(acetylamino)-1-[(4-
flurophenyl) carbonyl]-1H-indole-3-carboxylic acid, 1-[(4-fluorophenyl) carbonyl]-5 …

In the present work Indole and substituted glycolic acid have been chosen as starting
materials. These are broad class of chemical compounds, with many important …

Indoles and their derivatives find a prominent place in synthetic organic chemistry, as they
are found to be potent pharmacophores. They have been reported to possess a wide variety …

Background: Five-membered heterocycle with one neighbouring nitrogen atoms is present
in the indole nucleus. Heterocyclic substances feature two adjacent benzene and pyrrole …

Purpose: Long-term clinical usage of nonsteroidal anti-inflammatory drugs (NSAIDs) is
associated with significant side effects-gastrointestinal lesions, bleeding and nephrotoxicity …

Non steroidal anti-inflammatory agents (NSAIDs) continue to be one of the most widely used
groups of therapeutic agents. NSAIDs cause several serious adverse effects; the most …

Indole, the bicyclic ring system consists of pyrrole ring fused with benzene ring. Although
indole moiety is very small but is fascinated by scientists because of the diverse biological …