Serum complement opsonizes particles such as bacteria for clearance by the
reticuloendothelial system. Complement has been reported to interact with liposomes and …

We have studied the complement-activating properties of liposomes. We show that surface
charge is a key determinant of complement-activating liposomes. The nature of the charge …

Publisher Summary This chapter describes some basic principles and details of the most
widely used experimental methods in studying the interaction of liposomes with the …

We have investigated the contribution of immunoglobulin to the liposome-induced activation
of complement in human serum. Liposomes containing the negatively charged …

Complement activation causes opsonization of foreign particles leading to particle
elimination from the blood. Complement-mediated opsonization of charged and large …

Liposomal model membranes were found to activate the alternative pathway of human
complement. Activation was measured by C3 conversion and component consumption in …

The activation of complement results in the opsonization of particles for removal by the
reticuloendothelial system. Experimental evidence suggests that complement-mediated …

We have previously reported that complement-opsonized liposomes composed of
dimyristoyl phosphatidylcholine and cholesterol are actively phagocytozed by murine …

Ingestion of liposomes opsonized by specific antibody plus complement was investigated in
vitro. Although the antibodies alone (IgM) did not have an opsonizing effect, in the presence …

Activation of complement (C) by haptenized liposomes has been utilized for a long time to
study the interaction of biological membranes with C proteins, or as a sensitive …