Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts
Mitogen-activated protein kinases (p42mapk and p44mapk) are serine/threonine kinases
that are activated rapidly in cells stimulated with various extracellular signals. This activation …
that are activated rapidly in cells stimulated with various extracellular signals. This activation …
Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation.
G Pages, P Lenormand, G L'Allemain… - Proceedings of the …, 1993 - National Acad Sciences
The mitogen-activated protein kinases (MAP kinases) p42mapk and p44mapk are
serine/threonine kinases rapidly activated in cells stimulated with various extracellular …
serine/threonine kinases rapidly activated in cells stimulated with various extracellular …
[HTML][HTML] Signal transduction within the nucleus by mitogen-activated protein kinase.
A Seth, FA Gonzalez, S Gupta, DL Raden… - Journal of Biological …, 1992 - Elsevier
The nucleus is an important target of signal transduction by growth factor receptors that
stimulate mitogen-activated protein (MAP) kinases. We tested the hypothesis that MAP …
stimulate mitogen-activated protein (MAP) kinases. We tested the hypothesis that MAP …
[HTML][HTML] Nuclear translocation of p42/p44 mitogen‐activated protein kinase is required for growth factor‐induced gene expression and cell cycle entry
A Brunet, D Roux, P Lenormand, S Dowd… - The EMBO …, 1999 - embopress.org
Mitogen‐activated protein kinase (MAPK) modules, composed of three protein kinases
activated by successive phosphorylation, are involved in the signal transduction of a wide …
activated by successive phosphorylation, are involved in the signal transduction of a wide …
Mitogen-activated protein kinase kinase activity is required for the G2/M transition of the cell cycle in mammalian fibroblasts
JH Wright, E Munar, DR Jameson… - Proceedings of the …, 1999 - National Acad Sciences
The mitogen-activated protein kinase (MAPK) cascade is required for mitogenesis in somatic
mammalian cells and is activated by a wide variety of oncogenic stimuli. Specific roles for …
mammalian cells and is activated by a wide variety of oncogenic stimuli. Specific roles for …
Cell cycle reentry of mammalian fibroblasts is accompanied by the sustained activation of P44mapk and P42mapk isoforms in the G1 phase and their inactivation at …
S Meloche - Journal of cellular physiology, 1995 - Wiley Online Library
Mitogen‐activated protein (MAP) kinases are serine/threonine kinases that are rapidly
activated in response to mitogenic stimuli. Here we examined the enzymatic activity and …
activated in response to mitogenic stimuli. Here we examined the enzymatic activity and …
Constitutive mutant and putative regulatory serine phosphorylation site of mammalian MAP kinase kinase (MEK1).
In response to various external stimuli, MAP kinases are activated by phosphorylation on
tyrosine and threonine by MAP kinase kinase (MAPKK), a dual specificity kinase. This …
tyrosine and threonine by MAP kinase kinase (MAPKK), a dual specificity kinase. This …
Constitutive MAP kinase phosphatase (MKP-1) expression blocks G1 specific gene transcription and S-phase entry in fibroblasts.
JM Brondello, FR McKenzie, H Sun, NK Tonks… - Oncogene, 1995 - europepmc.org
MAP kinase (mitogen activated protein kinase) represents a ubiquitously expressed family of
kinases whose long term activation via phosphorylation is essential for the mitogenic …
kinases whose long term activation via phosphorylation is essential for the mitogenic …
Identification and characterization of a new mammalian mitogen-activated protein kinase kinase, MKK2
J Wu, JK Harrison, P Dent, KR Lynch… - … and cellular biology, 1993 - Taylor & Francis
Mitogen-activated protein (MAP) kinases are serine/threonine protein kinases activated by
dual phosphorylation on threonine and tyrosine residues. A MAP kinase kinase (MKK1 or …
dual phosphorylation on threonine and tyrosine residues. A MAP kinase kinase (MKK1 or …
Functional expression and growth factor activation of an epitope-tagged p44 mitogen-activated protein kinase, p44mapk.
Mitogen-activated protein kinases (MAPKs) or extracellular signal-regulated kinases (ERKs)
are serine/threonine kinases of apparent Mr 42-44 kDa that are rapidly activated by a variety …
are serine/threonine kinases of apparent Mr 42-44 kDa that are rapidly activated by a variety …
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