A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci

Y Liu, C Helms, W Liao, LC Zaba, S Duan… - PLoS …, 2008 - journals.plos.org
A genome-wide association study was performed to identify genetic factors involved in
susceptibility to psoriasis (PS) and psoriatic arthritis (PSA), inflammatory diseases of the skin …

Genome-wide association analysis of psoriatic arthritis and cutaneous psoriasis reveals differences in their genetic architecture

PE Stuart, RP Nair, LC Tsoi, T Tejasvi, S Das… - The American Journal of …, 2015 - cell.com
Psoriasis vulgaris (PsV) is a common inflammatory and hyperproliferative skin disease. Up
to 30% of people with PsV eventually develop psoriatic arthritis (PsA), an inflammatory …

Genetic epidemiology of psoriasis and psoriatic arthritis

P Rahman, JT Elder - Annals of the rheumatic diseases, 2005 - ard.bmj.com
Psoriasis and psoriatic arthritis (PsA) are interrelated disorders, as most patients with PsA
also have psoriasis. Thus it is not surprising that epidemiological and immunogenetic …

[HTML][HTML] Genome-wide meta-analysis of psoriatic arthritis identifies susceptibility locus at REL

E Ellinghaus, PE Stuart, D Ellinghaus, RP Nair… - Journal of Investigative …, 2012 - Elsevier
Psoriatic arthritis (PsA) is a chronic inflammatory musculoskeletal disease affecting up to
30% of psoriasis vulgaris (PsV) cases and approximately 0.25 to 1% of the general …

Genome-wide association scan yields new insights into the immunopathogenesis of psoriasis

JT Elder - Genes & Immunity, 2009 - nature.com
Psoriasis is a common, immunologically mediated, inflammatory and hyperproliferative
disease of the skin and joints, with a multifactorial genetic basis. We earlier mapped …

Evidence to support IL-13 as a risk locus for psoriatic arthritis but not psoriasis vulgaris

J Bowes, S Eyre, E Flynn, P Ho, S Salah… - Annals of the …, 2011 - ard.bmj.com
Objective There is great interest in the identification of genetic factors that differentiate
psoriatic arthritis (PsA) from psoriasis vulgaris (PsV), as such discoveries could lead to the …

Genetic, epigenetic and pharmacogenetic aspects of psoriasis and psoriatic arthritis

DD O'Rielly, P Rahman - Rheumatic Disease Clinics, 2015 - rheumatic.theclinics.com
Clinicians have long recognized a strong familial component to psoriatic disease, and this
observation has been substantiated in population and cohort-based studies. Epidemiologic …

Investigation of association of the IL12B and IL23R genes with psoriatic arthritis

C Filer, P Ho, RL Smith, C Griffiths… - … : Official Journal of …, 2008 - Wiley Online Library
Objective Recent reports have confirmed association of single‐nucleotide polymorphisms
(SNPs) mapping to the interleukin‐23 receptor (IL‐23R) and IL‐12β genes with psoriasis …

The genetics of psoriasis and psoriatic arthritis

V Chandran - Clinical reviews in allergy & immunology, 2013 - Springer
Genetic epidemiological studies have demonstrated a significant genetic basis to both
psoriasis and psoriatic arthritis (PsA). Although candidate gene association studies had …

Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis

J Bowes, A Budu-Aggrey, U Huffmeier, S Uebe… - Nature …, 2015 - nature.com
Psoriatic arthritis (PsA) is a chronic inflammatory arthritis associated with psoriasis and,
despite the larger estimated heritability for PsA, the majority of genetic susceptibility loci …