Isobaric labeling empowers proteome-wide expression measurements simultaneously
across multiple samples. Here an expanded set of 16 isobaric reagents based on an …

The development of the TMTpro-16plex series expanded the breadth of commercial isobaric
tagging reagents by nearly 50% over classic TMT-11plex. In addition to the described …

Isobaric stable isotope labeling using, for example, tandem mass tags (TMTs) is increasingly
being applied for large-scale proteomic studies. Experiments focusing on proteoform …

Quantitative mass spectrometry methods offer near-comprehensive proteome coverage;
however, these methods still suffer with regards to sample throughput. Multiplex quantitation …

Isobaric mass tag-based quantitative proteomics strategies such as iTRAQ and TMT utilize
reporter ions in the low-mass range of tandem MS spectra for relative quantification. The …

We describe a mass spectrometry method, QuantMode, which improves accuracy of isobaric
tag–based quantification by alleviating the pervasive problem of precursor interference …

Mass spectrometry based proteomics can routinely identify hundreds of proteins in a single
LC-MS run, and methods have been developed for relative quantitation between …

Multiplex isobaric tags (eg, tandem mass tags (TMT) and isobaric tags for relative and
absolute quantification (iTRAQ)) are a valuable tool for high-throughput mass spectrometry …

The multiplexing capabilities of isobaric mass tag-based protein quantification, such as
Tandem Mass Tags or Isobaric Tag for Relative and Absolute Quantitation have dramatically …

We developed EASI-tag (easily abstractable sulfoxide-based isobaric-tag), a new type of
amine-derivatizing and sulfoxide-containing isobaric labeling reagents for highly accurate …