Transcriptional regulation via the NF-κB signaling module
Stimulus-induced nuclear factor-κB (NF-κB) activity, the central mediator of inflammatory
responses and immune function, comprises a family of dimeric transcription factors that …
responses and immune function, comprises a family of dimeric transcription factors that …
Specification of DNA binding activity of NF-κB proteins
F Wan, MJ Lenardo - Cold Spring Harbor perspectives in …, 2009 - cshperspectives.cshlp.org
Nuclear factor-κB (NF-κB) is a pleiotropic mediator of inducible and specific gene regulation
involving diverse biological activities including immune response, inflammation, cell …
involving diverse biological activities including immune response, inflammation, cell …
Diversity and regulation in the NF-κB system
C Wietek, LAJ O'Neill - Trends in biochemical sciences, 2007 - cell.com
The nuclear factor (NF)-κB family of transcription factors is a key participant in multiple
biological processes, most notably in the immune and inflammatory response. Five proteins …
biological processes, most notably in the immune and inflammatory response. Five proteins …
The NF-κB family of transcription factors and its regulation
A Oeckinghaus, S Ghosh - Cold Spring Harbor …, 2009 - cshperspectives.cshlp.org
Nuclear factor-κB (NF-κB) consists of a family of transcription factors that play critical roles in
inflammation, immunity, cell proliferation, differentiation, and survival. Inducible NF-κB …
inflammation, immunity, cell proliferation, differentiation, and survival. Inducible NF-κB …
New insights into NF-κB regulation and function
NF-κB (nuclear factor-κB) transcription factors have multiple critical roles in the regulation of
immune responses. In unstimulated cells, NF-κB proteins are sequestered in the cytoplasm …
immune responses. In unstimulated cells, NF-κB proteins are sequestered in the cytoplasm …
Posttranslational modifications of NF-κB: another layer of regulation for NF-κB signaling pathway
The eukaryotic transcription factor NF-κB regulates a wide range of host genes that control
the inflammatory and immune responses, programmed cell death, cell proliferation and …
the inflammatory and immune responses, programmed cell death, cell proliferation and …
IκB-independent control of NF-κB activity by modulatory phosphorylations
ML Schmitz, S Bacher, M Kracht - Trends in biochemical sciences, 2001 - cell.com
Activation of the transcription factor nuclear factor κB (NF-κB) requires its release from
inhibitor of NF-κB (IκB) proteins in the cytoplasm. Much work has focussed on the …
inhibitor of NF-κB (IκB) proteins in the cytoplasm. Much work has focussed on the …
NF‐κB: a multifaceted transcription factor regulated at several levels
ML Schmitz, I Mattioli, H Buss, M Kracht - Chembiochem, 2004 - Wiley Online Library
NF‐κB is a generic name for an evolutionarily conserved transcription‐factor system that
contributes to the mounting of an effective immune response but is also involved in the …
contributes to the mounting of an effective immune response but is also involved in the …
Crosstalk via the NF-κB signaling system
S Basak, A Hoffmann - Cytokine & growth factor reviews, 2008 - Elsevier
The nuclear factor kappaB (NF-κB) family of transcription factors consists of 15 possible
dimers whose activity is controlled by a family of inhibitor proteins, known as IκBs. A variety …
dimers whose activity is controlled by a family of inhibitor proteins, known as IκBs. A variety …
A structural guide to proteins of the NF-κB signaling module
The prosurvival transcription factor NF-κB specifically binds promoter DNA to activate target
gene expression. NF-κB is regulated through interactions with IκB inhibitor proteins. Active …
gene expression. NF-κB is regulated through interactions with IκB inhibitor proteins. Active …
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