Chronic wounds are a major complication of diabetes associated with high morbidity and
health care expenditures. To investigate the role of colonizing microbiota in diabetic wound …

The wound microbiome consists of living microbial communities (“microbiota”) that interact
with each other and their surroundings in the injured tissue. The role of the wound …

Chronic, non-healing wounds are a major complication of diabetes associated with high
morbidity and health care expenditures estimated at $9-13 billion annually in the US …

Wound healing is a highly coordinated and complex process, and there can be devastating
consequences if it is interrupted. It is believed that, in combination with host factors …

World Health Organization considered diabetes as one of the 20th century epidemics,
estimating that over 10% of the world population is diabetic or at high risk. Self-assessment …

Microbial burden of chronic wounds is believed to play an important role in impaired healing
and the development of infection-related complications. However, clinical cultures have little …

Purpose. While some micro-organisms, such as Staphylococcus aureus, are clearly
implicated in causing tissue damage in diabetic foot ulcers (DFUs), our knowledge of the …

Diabetics frequently suffer from chronic, nonhealing wounds. Although bacterial colonization
and/or infection are generally acknowledged to negatively impact wound healing, the …

Nonhealing diabetic foot ulcers (DFUs) are a common and costly complication of diabetes.
Microbial burden, or “bioburden,” is believed to underlie delayed healing, although little is …

Diabetics chronic wounds are characterized by high levels of oxidative stress (OS) and are
often colonized by biofilm-forming bacteria that severely compromise healing and can result …