Inflammatory bowel diseases are characterized by dysregulated immune response to the
normal microflora and structural and functional changes of the enteric nervous system which …

AIM: To characterise expression of interleukin 6 (IL-6), a potent proinflammatory cytokine, in
the occurrence and development of inflammatory bowel disease (IBD) and investigate its …

The intestinal mucosa is in a constant state of controlled inflammation, but the processes
whereby this occurs are poorly understood. The aims of this study were to look at the role of …

Fos expression was used to assess whether the proinflammatory cytokine interleukin-1β (IL-
1β) activated specific, chemically coded neuronal populations in isolated preparations of …

Local inflammation in the colon has been associated with nutrient malabsorption and altered
motility in the small bowel. These remote effects suggest the release of mediators which can …

BACKGROUND & AIMS: Distal colitis induced in rats by trinitrobenzene sulfonic acid (TNBS)
causes a suppression of [3H] noradrenaline release from the myenteric plexus, of inflamed …

Background & Aims: Sensory neuropeptides modulate the mucosal response to
inflammation in experimental colitis. Because nerve growth factor (NGF) regulates the …

Intestinal epithelial cells may be actively involved in the immunoregulatory pathways leading
to intestinal inflammation. The aim of this study was to assess expression by intestinal …

Background Gut dysmotility is closely associated with proinflammatory cytokines both in
irritable bowel syndrome and inflammatory bowel disease. There is a dose–response …

Background & Aims: Studies in inflammatory bowel disease have shown extensive structural
abnormalities in the enteric nervous system of inflamed and noninflamed gut; however …