[HTML][HTML] Peli1 signaling blockade attenuates congenital zika syndrome

H Luo, G Li, B Wang, B Tian, J Gao, J Zou, S Shi… - PLoS …, 2020 - journals.plos.org
Zika virus (ZIKV) infects pregnant women and causes devastating congenital zika syndrome
(CZS). How the virus is vertically transmitted to the fetus and induces neuronal loss remains …

[HTML][HTML] Jak inhibitors modulate production of replication-competent zika virus in human hofbauer, trophoblasts, and neuroblastoma cells

C Gavegnano, LC Bassit, BD Cox, HM Hsiao… - Pathogens & …, 2017 - ncbi.nlm.nih.gov
Zika Virus (ZIKV) is a flavivirus that has been implicated in causing brain deformations, birth
defects, and microcephaly in fetuses, and associated with Guillain-Barre syndrome …

Zika virus causes placental pyroptosis and associated adverse fetal outcomes by activating GSDME

Z Zhao, Q Li, U Ashraf, M Yang, W Zhu, J Gu, Z Chen… - Elife, 2022 - elifesciences.org
Zika virus (ZIKV) can be transmitted from mother to fetus during pregnancy, causing adverse
fetal outcomes. Several studies have indicated that ZIKV can damage the fetal brain directly; …

Zika virus depletes neural stem cells and evades selective autophagy by suppressing the Fanconi anemia protein FANCC

SK Tiwari, JW Dang, N Lin, Y Qin, S Wang… - EMBO reports, 2020 - embopress.org
Zika virus (ZIKV) is an emerging flavivirus, which when passed through vertical transmission
from mother to developing fetus can lead to developmental abnormalities, including …

Zika virus infection disrupts neurovascular development and results in postnatal microcephaly with brain damage

Q Shao, S Herrlinger, SL Yang, F Lai… - …, 2016 - journals.biologists.com
Zika virus (ZIKV) infection of pregnant women can result in fetal brain abnormalities. It has
been established that ZIKV disrupts neural progenitor cells (NPCs) and leads to embryonic …

[HTML][HTML] Preventive effects of folic acid on Zika virus-associated poor pregnancy outcomes in immunocompromised mice

Y Simanjuntak, HY Ko, YL Lee, GY Yu, YL Lin - PLoS Pathogens, 2020 - journals.plos.org
Zika virus (ZIKV) infection may lead to congenital microcephaly and pregnancy loss in
pregnant women. In the context of pregnancy, folic acid (FA) supplementation may reduce …

[HTML][HTML] Zika virus NS4A and NS4B proteins deregulate Akt-mTOR signaling in human fetal neural stem cells to inhibit neurogenesis and induce autophagy

Q Liang, Z Luo, J Zeng, W Chen, SS Foo, SA Lee, J Ge… - Cell stem cell, 2016 - cell.com
The current widespread outbreak of Zika virus (ZIKV) infection has been linked to severe
clinical birth defects, particularly microcephaly, warranting urgent study of the molecular …

[HTML][HTML] Zika virus pathogenesis: a battle for immune evasion

J Estévez-Herrera, S Pérez-Yanes… - Vaccines, 2021 - mdpi.com
Zika virus (ZIKV) infection and its associated congenital and other neurological disorders,
particularly microcephaly and other fetal developmental abnormalities, constitute a World …

Dysregulation of Ephrin receptor and PPAR signaling pathways in neural progenitor cells infected by Zika virus

SN Thulasi Raman, E Latreille, J Gao… - Emerging microbes & …, 2020 - Taylor & Francis
Zika virus (ZIKV) infection is a serious public threat with cases reported in about 70 countries
and territories. One of the most serious consequences of ZIKV infection is congenital …

Neural progenitor cell pyroptosis contributes to Zika virus-induced brain atrophy and represents a therapeutic target

Z He, S An, J Chen, S Zhang, C Tan… - Proceedings of the …, 2020 - National Acad Sciences
Mounting evidence has associated Zika virus (ZIKV) infection with congenital malformations,
including microcephaly, which raises global alarm. Nonetheless, mechanisms by which …