[PDF][PDF] Intraocular biodistribution of intravitreal injected chitosan/gelatin nanoparticles

AD Moraru, M Costuleanu, A Sava, DŢ Costin… - Rom. J. Morphol …, 2014 - rjme.ro
The aim of this study was to evaluate intraocular biodistribution of a fluorescent polymeric
nanosystem composed of chitosan and gelatin after intravitreal administration in rat eyes …

Intraocular biodistribution of intravitreal injected fluorescent dexamethasone-chitosan nanoparticles in rabbit eyes

AD Moraru, M Costuleanu, D Costin, C Peptu… - The Medical-Surgical …, 2015 - revmedchir.ro
Aim: To evaluate intraocular biodistribution of fluorescent nanoparticles composed of
dexamethasone bound to chitosan after intravitreal administration in rabbit eyes. Material …

Double cross-linked chitosan—gelatin particulate systems for ophthalmic applications

CA Peptu, G Buhus, M Popa… - Journal of bioactive …, 2010 - journals.sagepub.com
Gelatin/chitosan particles suitable for application in ocular drug administration were
prepared by a two-step cross-linking process performed in an emulsion-phase separation …

Chitosan Nanoparticles as New Ocular Drug Delivery Systems: in Vitro Stability, in Vivo Fate, and Cellular Toxicity

AM de Campos, Y Diebold, ELS Carvalho… - Pharmaceutical …, 2004 - Springer
Purpose. To assess the potential of chitosan (CS) nanoparticles for ocular drug delivery by
investigating their interaction with the ocular mucosa in vivo and also their toxicity in …

The movement of self-assembled amphiphilic polymeric nanoparticles in the vitreous and retina after intravitreal injection

H Koo, H Moon, H Han, JH Na, MS Huh, JH Park… - Biomaterials, 2012 - Elsevier
The purpose of this study is to determine the correlation between the distribution of
nanoparticles in the vitreous and retina and their surface properties after intravitreal …

Chitosan coated sodium alginate–chitosan nanoparticles loaded with 5-FU for ocular delivery: In vitro characterization and in vivo study in rabbit eye

RC Nagarwal, R Kumar, JK Pandit - European Journal of Pharmaceutical …, 2012 - Elsevier
The objective of the study was to develop chitosan (CH) coated sodium alginate–chitosan
(SA–CH) nanoparticles, ie CH-SA–CH NPs loaded with 5-FU for ophthalmic delivery. Drug …

Biofabrication of chitosan-based nanomedicines and its potential use for translational ophthalmic applications

R Vichare, I Garner, RJ Paulson, R Tzekov, N Sahiner… - Applied Sciences, 2020 - mdpi.com
Drug delivery to the anterior and posterior segment of eye remains a challenge.
Nanoparticle-mediated drug delivery has indicated some promise. The presented review …

Chitosan microparticles for delivery of proteins to the retina

S Wassmer, M Rafat, WG Fong, AN Baker, C Tsilfidis - Acta biomaterialia, 2013 - Elsevier
Chitosan microparticles (CMPs) have previously been developed for topical applications to
the eye, but their safety and efficacy in delivering proteins to the retina have not been …

[HTML][HTML] Biodistribution of cy5-labeled thiolated and methylated chitosan-carboxymethyl dextran nanoparticles in an animal model of retinoblastoma

E Delrish, F Ghassemi, M Jabbarvand… - Journal of Ophthalmic …, 2022 - ncbi.nlm.nih.gov
Purpose The use of more potent medicine for local chemotherapy of retinoblastoma in order
to minimize local and systemic adverse effects is essential. The main goal of this …

Preparation and evaluation of chitosan–itraconazole co-precipitated nanosuspension for ocular delivery

M Ahuja, P Verma, M Bhatia - Journal of experimental …, 2015 - Taylor & Francis
The purpose of the present study was to prepare itraconazole-loaded chitosan
nanosuspension and evaluate it for ocular delivery. Itraconazole-loaded chitosan …