[HTML][HTML] The checkpoint protein Zw10 connects CAL1-dependent CENP-A centromeric loading and mitosis duration in Drosophila cells

AL Pauleau, A Bergner, J Kajtez, S Erhardt - PLoS Genetics, 2019 - journals.plos.org
A defining feature of centromeres is the presence of the histone H3 variant CENP-A that
replaces H3 in a subset of centromeric nucleosomes. In Drosophila cultured cells CENP-A …

BubR1 and CENP-E have antagonistic effects upon the stability of microtubule-kinetochore attachments in Drosophila S2 cell mitosis

AF Maia, CS Lopes, CE Sunkel - Cell Cycle, 2007 - Taylor & Francis
The Spindle Assembly Checkpoint ensures the fidelity of chromosome segregation at each
cell division cycle. Previous reports have indicated that in higher eukaryotes checkpoint …

[HTML][HTML] Drosophila CENP-A Mutations Cause a BubR1- Dependent Early Mitotic Delay without Normal Localization of Kinetochore Components

MD Blower, T Daigle, T Kaufman, GH Karpen - PLoS genetics, 2006 - journals.plos.org
The centromere/kinetochore complex plays an essential role in cell and organismal viability
by ensuring chromosome movements during mitosis and meiosis. The kinetochore also …

[HTML][HTML] A Conserved Arginine-Rich Motif within the Hypervariable N-Domain of Drosophila Centromeric Histone H3 (CenH3CID) Mediates BubR1 Recruitment

M Torras-Llort, S Medina-Giro, O Moreno-Moreno… - PloS one, 2010 - journals.plos.org
Background Centromere identity is determined epigenetically by deposition of CenH3, a
centromere-specific histone H3 variant that dictates kinetochore assembly. The molecular …

Drosophila CENP-C is essential for centromere identity

B Orr, CE Sunkel - Chromosoma, 2011 - Springer
Centromeres are specialized chromosomal domains that direct mitotic kinetochore assembly
and are defined by the presence of CENP-A (CID in Drosophila) and CENP-C. While the …

CRL4RBBP7 is required for efficient CENP‐A deposition at centromeres

J Mouysset, S Gilberto, MG Meier… - Journal of cell …, 2015 - journals.biologists.com
The mitotic spindle drives chromosome movement during mitosis and attaches to
chromosomes at dedicated genomic loci named centromeres. Centromeres are …

Two distinct pathways responsible for the loading of CENP-A to centromeres in the fission yeast cell cycle

K Takahashi, Y Takayama… - … of the Royal …, 2005 - royalsocietypublishing.org
CENP-A is a centromere-specific histone H3 variant that is-essential for faithful chromosome
segregation in all eukaryotes thus far investigated. We genetically identified two factors …

[HTML][HTML] CSN5/JAB1 interacts with the centromeric components CENP-T and CENP-W and regulates their proteasome-mediated degradation

Y Chun, M Lee, B Park, S Lee - Journal of Biological Chemistry, 2013 - ASBMB
The CENP-T· CENP-W complex is a recently identified inner centromere component that
plays crucial roles in the formation of a functional kinetochore involved in cell division during …

Tumor suppressor roles of CENP-E and Nsl1 in Drosophila epithelial tissues

M Clemente-Ruiz, M Muzzopappa, M Milán - Cell cycle, 2014 - Taylor & Francis
Depletion of spindle assembly checkpoint (SAC) genes in Drosophila epithelial tissues
leads to JNK-dependent programmed cell death and additional blockade of the apoptotic …

Mitotic checkpoint gene expression is tuned by codon usage bias

E Esposito, DE Weidemann, JM Rogers… - The EMBO …, 2022 - embopress.org
The mitotic checkpoint (also called spindle assembly checkpoint, SAC) is a signaling
pathway that safeguards proper chromosome segregation. Correct functioning of the SAC …