An overload of missense variants in the OTOG gene may drive a higher prevalence of familial Meniere disease in the European descendant population
JA Lopez-Escamez, AM Parra-Perez… - 2023 - researchsquare.com
Meniere's disease is a complex inner ear disorder with significant familial aggregation. A
differential prevalence of familial MD (FMD) has been reported, being 9-10% in Europeans …
differential prevalence of familial MD (FMD) has been reported, being 9-10% in Europeans …
Rare Variants in the OTOG Gene Are a Frequent Cause of Familial Meniere's Disease
Objectives Meniere's disease (MD) is a rare inner ear disorder characterized by
sensorineural hearing loss, episodic vertigo and tinnitus. Familial MD has been reported in 6 …
sensorineural hearing loss, episodic vertigo and tinnitus. Familial MD has been reported in 6 …
Burden of rare variants in the OTOG gene in familial Meniere's disease
P Roman-Naranjo, A Gallego-Martinez… - Ear and …, 2020 - journals.lww.com
Objectives: Meniere's disease (MD) is a rare inner ear disorder characterized by
sensorineural hearing loss, episodic vertigo, and tinnitus. Familial MD has been reported in …
sensorineural hearing loss, episodic vertigo, and tinnitus. Familial MD has been reported in …
[HTML][HTML] An overload of missense variants in the OTOG gene may drive a higher prevalence of familial Meniere disease in the European population
AM Parra-Perez, A Gallego-Martinez… - Human Genetics, 2024 - Springer
Meniere disease is a complex inner ear disorder with significant familial aggregation. A
differential prevalence of familial MD (FMD) has been reported, being 9–10% in Europeans …
differential prevalence of familial MD (FMD) has been reported, being 9–10% in Europeans …
Genetic architecture of Meniere's disease
A Gallego-Martinez, JA Lopez-Escamez - Hearing Research, 2020 - Elsevier
Meniere's disease (MD) is a complex disorder of the inner ear that causes vertigo attacks,
fluctuating sensorineural hearing loss (SNHL), tinnitus and aural fullness. MD has been …
fluctuating sensorineural hearing loss (SNHL), tinnitus and aural fullness. MD has been …
[HTML][HTML] Clinical and molecular genetics of Meniere disease
E Martinez-Gomez, A Gallego-Martinez… - Medizinische …, 2020 - degruyter.com
Meniere disease (MD) represents a heterogeneous group of relatively rare disorders of the
inner ear that causes vertigo attacks, fluctuating sensorineural hearing loss (SNHL) …
inner ear that causes vertigo attacks, fluctuating sensorineural hearing loss (SNHL) …
[PDF][PDF] Discovery in the genetics of complex disease: Otitis media
SE Jamieson - ENT & Audiology News, 2014 - entandaudiologynews.com
ENT FEATURE the role of middle ear hypoxia in OM and points to molecules that target
hypoxia-mediated pathways as potential novel therapies to alleviate middle ear hypoxia …
hypoxia-mediated pathways as potential novel therapies to alleviate middle ear hypoxia …
A novel early truncation mutation in OTOG causes prelingual mild hearing loss without vestibular dysfunction
OTOG was identified as a nonsyndrmoic hearing loss gene in 2012 in two families with
nonprogressive mild-to-moderate hearing loss. However, no further literature have this gene …
nonprogressive mild-to-moderate hearing loss. However, no further literature have this gene …
[HTML][HTML] Types of inheritance and genes associated with familial Meniere disease
AM Parra-Perez, JA Lopez-Escamez - … of the Association for Research in …, 2023 - Springer
Meniere disease (MD) is a rare disorder of the inner ear defined by sensorineural hearing
loss (SNHL) associated with episodes of vertigo and tinnitus. The phenotype is variable, and …
loss (SNHL) associated with episodes of vertigo and tinnitus. The phenotype is variable, and …
Aggregated variant analysis in exomes from familial and early onset Meniere disease patients
P Román-Naranjo Varela - 2020 - produccioncientifica.ugr.es
Introducción: La enfermedad de Meniere (EM) es una enfermedad rara del oído interno
caracterizada por hipoacusia neurosensorial, vértigo episódico, y tinnitus. Aunque la …
caracterizada por hipoacusia neurosensorial, vértigo episódico, y tinnitus. Aunque la …
相关搜索
- missense variants meniere disease
- otog gene meniere disease
- otog gene higher prevalence
- higher prevalence meniere disease
- otog gene missense variants
- higher prevalence missense variants
- european population meniere disease
- higher prevalence european population
- otog gene european population
- european population missense variants
- otog gene frequent cause
- missense variant prediction and interpretation
- missense variant hearing loss
- otog gene rare variants
- otog gene descendant population
- descendant population meniere disease