An evaluation of the impact of antibiotic stewardship on reducing the use of high-risk antibiotics and its effect on the incidence of Clostridium difficile infection in …

MA Aldeyab, MP Kearney, MG Scott… - Journal of …, 2012 - academic.oup.com
Objectives To evaluate the impact of a high-risk antibiotic stewardship programme on
reducing antibiotic use and on hospital Clostridium difficile infection (CDI) incidence rates. A …

Impact of guidelines and enhanced antibiotic stewardship on reducing broad-spectrum antibiotic usage and its effect on incidence of Clostridium difficile infection

MJ Talpaert, G Gopal Rao, BS Cooper… - Journal of …, 2011 - academic.oup.com
Objectives To evaluate the impact of an 'intervention'consisting of revised antibiotic
guidelines for empirical treatment of common infections and enhanced stewardship on …

Effect of antibiotic stewardship programmes on Clostridium difficile incidence: a systematic review and meta-analysis

LM Feazel, A Malhotra, EN Perencevich… - Journal of …, 2014 - academic.oup.com
Objectives Despite vigorous infection control measures, Clostridium difficile continues to
cause significant disease burden. Antibiotic stewardship programmes (ASPs) may prevent …

[HTML][HTML] Impact of an intervention to control Clostridium difficile infection on hospital-and community-onset disease; an interrupted time series analysis

J Price, E Cheek, S Lippett, M Cubbon… - Clinical microbiology …, 2010 - Elsevier
Strategies to reduce rates of Clostridium difficile infection (CDI) generally recommend
isolation or cohorting of active cases and the reduced use of cephalosporin and quinolone …

Cumulative Antibiotic Exposures Over Time and the Risk of Clostridium difficile Infection

V Stevens, G Dumyati, LS Fine… - Clinical infectious …, 2011 - academic.oup.com
Background. Clostridium difficile infection (CDI) is a major cause of hospital-acquired
diarrhea and is most commonly associated with changes in normal intestinal flora caused by …

Effects of fluoroquinolone restriction (from 2007 to 2012) on Clostridium difficile infections: interrupted time-series analysis

JB Sarma, B Marshall, V Cleeve, D Tate… - Journal of Hospital …, 2015 - Elsevier
Background Antimicrobial stewardship is a key component in the reduction of healthcare-
associated infections, particularly Clostridium difficile infection (CDI). We successfully …

Temporal effects of antibiotic use and Clostridium difficile infections

N Vernaz, K Hill, S Leggeat, D Nathwani… - Journal of …, 2009 - academic.oup.com
Objectives We tested a previously published model for the analysis of the temporal
relationship between antibiotic use and the incidence of Clostridium difficile infection in a …

Decreasing Clostridium difficile infections by an antimicrobial stewardship program that reduces moxifloxacin use

JM Wenisch, S Equiluz-Bruck, M Fudel… - Antimicrobial agents …, 2014 - Am Soc Microbiol
Clostridium difficile infections (CDI) in hospitalized patients are known to be closely related
to antibiotic exposure. Although several substances can cause CDI, the risk differs between …

Impact of a Reduction in the Use of High-Risk Antibiotics on the Course of an Epidemic of Clostridium difficile-Associated Disease Caused by the Hypervirulent NAP1 …

L Valiquette, B Cossette, MP Garant… - Clinical Infectious …, 2007 - academic.oup.com
A series of measures were implemented, in a secondary/tertiary-care hospital in Quebec, to
control an epidemic of nosocomial Clostridium difficile-associated disease (n-CDAD) …

Multipronged intervention strategy to control an outbreak of Clostridium difficile infection (CDI) and its impact on the rates of CDI from 2002 to 2007

K Weiss, A Boisvert, M Chagnon… - Infection Control & …, 2009 - cambridge.org
Objective. At the end of 2002, a new, more virulent strain of Clostridium difficile, designated
BI/NAP1, was the cause of a massive outbreak of infection in the province of Quebec. This …