Nuclear factor κB signaling in atherogenesis

MPJ De Winther, E Kanters, G Kraal… - … , and vascular biology, 2005 - Am Heart Assoc
Atherosclerosis is an inflammatory disease, characterized by the accumulation of
macrophage-derived foam cells in the vessel wall and accompanied by the production of a …

Nuclear factor-κB activation as a pathological mechanism of lipid metabolism and atherosclerosis

XH Yu, XL Zheng, CK Tang - Advances in clinical chemistry, 2015 - Elsevier
Atherosclerosis is a chronic inflammatory disease of the arterial wall with lipid-laden lesions,
involving a complex interaction between multiple different cell types and cytokine networks …

Nuclear factor κB: a potential therapeutic target in atherosclerosis and thrombosis

C Monaco, E Paleolog - Cardiovascular research, 2004 - academic.oup.com
Cardiovascular diseases are the leading cause of morbidity and mortality in Western
countries. Atherosclerosis, the background for many cardiovascular diseases, is …

Canonical pathway of nuclear factor κB activation selectively regulates proinflammatory and prothrombotic responses in human atherosclerosis

C Monaco, E Andreakos, S Kiriakidis… - Proceedings of the …, 2004 - National Acad Sciences
Nuclear factor κB (NF-κB) activation has been observed in human atherosclerotic plaques
and is enhanced in unstable coronary plaques, but whether such activation has a protective …

The nuclear factor‐κB/inhibitor of kappa B autoregulatory system and atherosclerosis

BL Thurberg, T Collins - Current opinion in lipidology, 1998 - journals.lww.com
Nuclear factor‐κB is a ubiquitous transcription factor that can be activated by diverse
proatherogenic stimuli such as inflammatory cytokines, lipopolysaccharide, oxidant stress …

The transcription factor NF-κB and the regulation of vascular cell function

R De Martin, M Hoeth, R Hofer-Warbinek… - … , and vascular biology, 2000 - Am Heart Assoc
A variety of pathophysiological situations that affect cells of the vasculature, including
endothelial and smooth muscle cells, leads to the expression of genes such as adhesion …

The nuclear factor–kappa B pathway in atherosclerosis: a potential therapeutic target for atherothrombotic vascular disease

B Pamukcu, GYH Lip, E Shantsila - Thrombosis research, 2011 - Elsevier
Nuclear factor kappa B (NFκB) is a transcription factor belonging to 'Rel'family that
represents a crucial intracellular signal transduction system involved in several inflammatory …

NF-κB signaling at the crossroads of inflammation and atherogenesis: searching for new therapeutic links

I Pateras, C Giaginis, C Tsigris, E Patsouris… - Expert Opinion on …, 2014 - Taylor & Francis
Introduction: NF-κB is a protein complex acting as a primary transcription factor and fast
messenger to harmful cellular stimuli, including inflammation. Carotid atherosclerosis is an …

Inflammation meets oxidation: NF-κB as a mediator of initial lesion development in atherosclerosis

O Kutuk, H Basaga - Trends in molecular medicine, 2003 - cell.com
Transcription factor nuclear factor-κB (NF-κB) and its target genes are involved in the
pathogenesis of atherosclerosis, in addition to many other diseases. Monocyte recruitment …

Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB): a new potential therapeutic target in atherosclerosis?

J Dąbek, A Kułach, Z Gąsior - Pharmacological reports, 2010 - Elsevier
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a crucial
transcription factor that participates in a number of physiological and pathological …