Functional Analysis of 14 Genes That Constitute the Purine Catabolic Pathway in Bacillus subtilis and Evidence for a Novel Regulon Controlled by the PucR …

AC Schultz, P Nygaard, HH Saxild - Journal of bacteriology, 2001 - Am Soc Microbiol
The soil bacterium Bacillus subtilis has developed a highly controlled system for the
utilization of a diverse array of low-molecular-weight compounds as a nitrogen source when …

Transcription Analysis of the Bacillus subtilis PucR Regulon and Identification of a cis-Acting Sequence Required for PucR-Regulated Expression of Genes Involved …

L Beier, P Nygaard, H Jarmer, HH Saxild - Journal of bacteriology, 2002 - Am Soc Microbiol
ABSTRACT The PucR protein of Bacillus subtilis has previously been suggested to regulate
the expression of 15 genes, pucABCDE, pucFG, pucH, pucI, pucJKLM, pucR, and gde, all of …

Roles of PucR, GlnR, and TnrA in Regulating Expression of the Bacillus subtilisure P3 Promoter

JL Brandenburg, LV Wray Jr, L Beier… - Journal of …, 2002 - Am Soc Microbiol
Expression of the P3 promoter of the Bacillus subtilis ureABC operon is activated during
nitrogen-limited growth by PucR, the transcriptional regulator of the purine-degradative …

Definition of a Second Bacillus subtilis pur Regulon Comprising the pur and xpt-pbuX Operons plus pbuG, nupG (yxjA), and pbuE (ydhL)

LE Johansen, P Nygaard, C Lassen… - Journal of …, 2003 - Am Soc Microbiol
In Bacillus subtilis expression of genes or operons encoding enzymes and other proteins
involved in purine synthesis is affected by purine bases and nucleosides in the growth …

Definition of the Bacillus subtilis PurR operator using genetic and bioinformatic tools and expansion of the PurR regulon with glyA, guaC, pbuG, xpt-pbuX, yqhZ-folD …

HH Saxild, K Brunstedt, KI Nielsen, H Jarmer… - Journal of …, 2001 - Am Soc Microbiol
The expression of the pur operon, which encodes enzymes of the purine biosynthetic
pathway in Bacillus subtilis, is subject to control by the purR gene product (PurR) and …

The Purine Efflux Pump PbuE in Bacillus subtilis Modulates Expression of the PurR and G-Box (XptR) Regulons by Adjusting the Purine Base Pool Size

P Nygaard, HH Saxild - Journal of bacteriology, 2005 - Am Soc Microbiol
In Bacillus subtilis, the expression of genes encoding enzymes and other proteins involved
in purine de novo synthesis and salvage is affected by purine bases and …

Regulation of levels of purine biosynthetic enzymes in Bacillus subtilis: effects of changing purine nucleotide pools

HH Saxild, P Nygaard - Microbiology, 1991 - microbiologyresearch.org
The genes encoding the enzymes of IMP biosynthesis in Bacillus subtilis constitute the pur
operon, whereas the genes encoding GMP biosynthetic enzymes, guaA (GMP synthetase) …

A Role for a Highly Conserved Protein of Unknown Function in Regulation of Bacillus subtilis purA by the Purine Repressor

P Rappu, BS Shin, H Zalkin… - Journal of …, 1999 - Am Soc Microbiol
Regulation of the purine biosynthetic gene purA was examined by using a transcriptional
fusion to a luciferase reporter gene. Transcription was repressed about 10-fold by the …

Functional Dissection of the Bacillus subtilis pur Operator Site

AK Bera, J Zhu, H Zalkin, JL Smith - Journal of bacteriology, 2003 - Am Soc Microbiol
Bacillus subtilis PurR represses transcription of several genes involved in purine synthesis,
metabolism, and transport and cofactor synthesis. PurR binds specifically to DNAs …

Purine and pyrimidine salvage pathways

P Nygaard - Bacillus subtilis and Other Gram‐Positive Bacteria …, 1993 - Wiley Online Library
The first complete purine nucleotide formed in the purine biosynthetic pathway is IMP, which
is converted to AMP and GMP via two separate pathways. The pathways by which purine …