Upregulation of vascular endothelial growth factor expression in the kidney could be reversed following treadmill exercise training in type I diabetic rats

M Al-Jarrah, N Erekat, A Al Khatib - World Journal of Nephrology and …, 2014 - wjnu.org
Background: Nephropathy is a significant complication of diabetes mellitus, which is
associated with high morbidity and mortality. Exercise training has been shown to have …

Beneficial effects of previous exercise training on renal changes in streptozotocin-induced diabetic female rats

LSB Amaral, FA Silva, VB Correia… - Experimental …, 2016 - journals.sagepub.com
This study evaluated the effects of aerobic exercise performed both previously and after the
induction of diabetes mellitus on changes of renal function and structure in streptozotocin …

[HTML][HTML] Treadmill exercise training improves vascular endothelial growth factor expression in the cardiac muscle of type I diabetic rats

NS Erekat, MD Al-Jarrah, AJ Al Khatib - Cardiology research, 2014 - ncbi.nlm.nih.gov
Background Vascular endothelial growth factor (VEGF) expression is a potent mitogen for
endothelial cells that is involved in angiogenesis. Cardiac VEGF is decreased in many …

Combination of exercise and losartan enhances renoprotective and peripheral effects in spontaneously type 2 diabetes mellitus rats with nephropathy

A Tufescu, M Kanazawa, A Ishida, H Lu… - Journal of …, 2008 - journals.lww.com
Objectives We assessed the renal and peripheral effects of chronic exercise in a rat model of
diabetic nephropathy and the benefits of combined exercise and losartan. Methods …

[HTML][HTML] Role of vascular endothelial growth factor in diabetic nephropathy

DR Cha, NH Kim, JW Yoon, SK Jo, WY Cho, HK Kim… - Kidney International, 2000 - Elsevier
Role of vascular endothelial growth factor in diabetic nephropathy. Background Vascular
endothelial growth factor (VEGF) is a potent cytokine that is considered to be an important …

The effect of regular swim training with two different time periods on serum levels of NO, VEGF, and TGF-β1 in diabetic male rats

P Farzanegi - Pathobiology Research, 2017 - mjms.modares.ac.ir
Objective: Diabetes is known to accelerate endothelial cell dysfunction. Meanwhile, an
adequate physical activity is recommended as a nonpharmacological treatment. Hence, the …

[HTML][HTML] Chronic running exercise alleviates early progression of nephropathy with upregulation of nitric oxide synthases and suppression of glycation in Zucker …

D Ito, P Cao, T Kakihana, E Sato, C Suda, Y Muroya… - PloS one, 2015 - journals.plos.org
Exercise training is known to exert multiple beneficial effects including renal protection in
type 2 diabetes mellitus and obesity. However, the mechanisms regulating these actions …

Angiotensin II receptor blocker attenuates overexpression of vascular endothelial growth factor in diabetic podocytes

EY Lee, MS Shim, MJ Kim, SY Hong, YG Shin… - … & Molecular Medicine, 2004 - nature.com
VEGF expressed in glomerular podocytes, is known to increase vascular permeability to
macromolecules. Angiotensin II can stimulate the release of VEGF, and the protective effects …

Preventive effect of exercise training on diabetic kidney disease in ovariectomized rats with type 1 diabetes

CS Souza, BS de Sousa Oliveira… - Experimental …, 2019 - journals.sagepub.com
This study evaluated the effects of moderate regular physical exercise on lipid peroxidation,
inflammation and renal function and structure in streptozotocin (STZ)-induced …

Effect of aerobic training on diabetic nephropathy in a rat model of type 2 diabetes mellitus

JM Chiasera, KM Ward-Cook… - Annals of Clinical & …, 2000 - Assoc Clin Scientists
The effect of aerobic exercise intervention on the renal functional and ultrastructural
changes associated with diabetes mellitus were studied in the obese Zucker rat, a rat model …