In the mouse, over the last 20 years, a set of cell‐surface markers and activities have been
identified, enabling the isolation of bone marrow (BM) populations highly enriched in …

We have identified a population of cells in murine bone marrow that has many of the
phenotypic characteristics attributed to resting hematopoietic stem cells but does not …

Mouse hematopoietic stem cells (HSCs) are the best-studied stem cells because functional
assays for mouse HSCs were established earliest and purification techniques for mouse …

Hematopoietic stem cells (HSCs) have been extensively characterized based on functional
definitions determined by experimental transplantation into lethally irradiated mice. In mice …

The identification of adult‐derived stem cells which maintain plasticity throughout the course
of a lifetime, has transformed the field of stem cell biology. Bone marrow derived …

Hematopoietic stem cells (HSCs) are defined by the capabilities of multi-lineage
differentiation and long-term self-renewal. Both these characteristics contribute to maintain …

The hematopoietic stem cell (HSC) niche commonly refers to the pairing of hematopoietic
and mesenchymal cell populations that regulate HSC self-renewal, differentiation, and …

Hematopoietic stem cells (HSCs) are uniquely capable of self-renewal and provision of all of
the mature elements of the blood and immune system throughout the lifetime of an …

Ex vivo expansion of hematopoietic stem cells (HSCs) is important for many clinical
applications, and knowledge of the surface phenotype of ex vivo–expanded HSCs will be …

Utilizing multipotent and self-renewing capabilities, hematopoietic stem cells (HSCs) can
maintain hematopoiesis throughout life. However, the mechanism behind such remarkable …