Vitamin D and autoimmunity: new aetiological and therapeutic considerations

Y Arnson, H Amital, Y Shoenfeld - Annals of the rheumatic diseases, 2007 - ard.bmj.com
Vitamin D is frequently prescribed by rheumatologists to prevent and treat osteoporosis.
Several observations have shown that vitamin D inhibits proinflammatory processes by …

Vitamin D and autoimmune rheumatic diseases

L Athanassiou, I Kostoglou-Athanassiou, M Koutsilieris… - Biomolecules, 2023 - mdpi.com
Vitamin D is a steroid hormone with potent immune-modulating properties. It has been
shown to stimulate innate immunity and induce immune tolerance. Extensive research …

Vitamin D in rheumatoid arthritis—towards clinical application

LE Jeffery, K Raza, M Hewison - Nature Reviews Rheumatology, 2016 - nature.com
In addition to its well-documented involvement in mineral homeostasis, vitamin D seems to
have broad effects on human health that go beyond the skeletal system. Prominent among …

Vitamin D and autoimmune rheumatic diseases

M Cutolo - Rheumatology, 2009 - academic.oup.com
Vitamin D is classified as a secosteroid in which one of the rings has been broken, in this
case by ultraviolet B sunlight, and the main source of vitamin D is de novo synthesis in the …

Vitamin D and the immune system

N Maruotti, FP Cantatore - The Journal of rheumatology, 2010 - jrheum.org
Evidence of the role of vitamin D in the regulation of T and B cells, macrophages, dendritic
cells, and keratinocytes continues to accumulate and provides a link between vitamin D and …

Vitamin D in rheumatoid arthritis

M Cutolo, K Otsa, M Uprus, S Paolino, B Seriolo - Autoimmunity reviews, 2007 - Elsevier
The discovery of the vitamin D receptor (VDR) in the cells of the immune system and the fact
that activated dendritic cells produce the vitamin D hormone suggested that vitamin D could …

Vitamin D endocrine system and the immune response in rheumatic diseases

M Cutolo, M Plebani, Y Shoenfeld, L Adorini… - Vitamins & …, 2011 - Elsevier
Epidemiological evidence indicates a significant association between vitamin D deficiency
and an increased incidence of autoimmune diseases. The presence of vitamin D receptors …

Vitamin D deficiency is associated with an increased autoimmune response in healthy individuals and in patients with systemic lupus erythematosus

LL Ritterhouse, SR Crowe, TB Niewold… - Annals of the …, 2011 - ard.bmj.com
Objectives Vitamin D deficiency is widespread and has been associated with many chronic
diseases, including autoimmune disorders. A study was undertaken to explore the impact of …

Vitamin D deficiency and risk for rheumatic diseases: an update

P Gatenby, R Lucas… - Current opinion in …, 2013 - journals.lww.com
Vitamin D deficiency and risk for rheumatic diseases: an upd... : Current Opinion in
Rheumatology Vitamin D deficiency and risk for rheumatic diseases: an update : Current Opinion …

Vitamin D and inflammation

X Guillot, L Semerano, N Saidenberg-Kermanac'h… - Joint Bone Spine, 2010 - Elsevier
Calcitriol, or 1, 25-dihydroxyvitamin D3 (1, 25 (OH) 2D3) is a well-known endocrine regulator
of calcium homeostasis. More recently, local calcitriol production by immune cells was …