Depression is a leading contributor to the global burden of diseases. Despite advances in
research, challenges still exist in managing this disorder. Sufferers of autoimmune diseases …

Immune dysregulation is very common in major depression (MD) patients, with these
individuals incurring increased risk for development of chronic inflammatory disease or …

Depression has been characterized as a disorder of both immune suppression and immune
activation. Markers of impaired cellular immunity (decreased natural killer cell cytotoxicity) …

Since the inception of Brain, Behavior and Immunity twenty years ago, many exciting
developments have occurred regarding the relationship between depression and the …

Background. Autoimmune diseases are associated with substantial morbidity and mortality,
yet the etiology remains unclear. Depression has been implicated as a risk factor for various …

The relationship between depression and immunity has been widely discussed. Cytokines,
such as TNF-α, play an important role in immune system; these cytokines interact with …

When thinking about the role of inflammation in depression, it is tempting to envision a
monolithic immunologic process that nonspecifically affects multiple aspects of behavior …

The inflammation theory of depression, proposed over 20 years ago, was influenced by
early studies on T cell responses and since then has been a stimulus for numerous research …

The possibility that inflammation plays a causal role in major depression is an important
claim in the emerging field of immunopsychiatry and has generated hope for new …

Psychoneuroimmunology is a field that investigates the interactions between the brain and
the immune system. One important goal of this field of research is to translate basic research …