Conjunctival and corneal tolerability assessment of ocular naltrexone niosomes and their ingredients on the hen's egg chorioallantoic membrane and excised bovine …
This study aimed at combining the hen's egg test-chorioallantoic membrane (HET-CAM),
bovine corneal opacity and permeability (BCOP) test and histological examination of …
bovine corneal opacity and permeability (BCOP) test and histological examination of …
Design and evaluation of controlled-release niosomes and discomes for naltrexone hydrochloride ocular delivery
This study aimed at preparing and evaluating Span 60-based niosomes for ocular delivery
of naltrexone hydrochloride (NTX). Selected charged lipids [dicetyl phosphate (DCP) and …
of naltrexone hydrochloride (NTX). Selected charged lipids [dicetyl phosphate (DCP) and …
Preparation of niosomes as an ocular delivery system for naltrexone hydrochloride: physicochemical characterization
H Abdelkader, S Ismail, A Kamal… - Die Pharmazie-An …, 2010 - ingentaconnect.com
Recent reports have demonstrated that topical and systemic application of naltrexone
markedly improves the characteristic signs of diabetic keratopathy; most notably, impaired …
markedly improves the characteristic signs of diabetic keratopathy; most notably, impaired …
Niosomes and discomes for ocular delivery of naltrexone hydrochloride: morphological, rheological, spreading properties and photo-protective effects
Naltrexone hydrochloride (NTX) is a promising treatment for corneal disorders linked to
diabetes mellitus (diabetic keratopathy). However, NTX has a major stability problem due to …
diabetes mellitus (diabetic keratopathy). However, NTX has a major stability problem due to …
Preparation and evaluation of reverse-phase evaporation and multilamellar niosomes as ophthalmic carriers of acetazolamide
AS Guinedi, ND Mortada, S Mansour… - International journal of …, 2005 - Elsevier
Niosomes have been reported as a possible approach to improve the low corneal
penetration and bioavailability characteristics shown by conventional ophthalmic vehicles …
penetration and bioavailability characteristics shown by conventional ophthalmic vehicles …
Nonionic surfactant vesicles (niosomes) for ocular drug delivery: Development, evaluation and toxicological profiling
Niosomes are emerging drug delivery systems that maintain the drug targeting advantages
of liposomes, while overcoming the problems of low drug encapsulation and instabilities …
of liposomes, while overcoming the problems of low drug encapsulation and instabilities …
Development of a topical niosomal preparation of acetazolamide: preparation and evaluation
D Aggarwal, A Garg, IP Kaur - Journal of Pharmacy and …, 2004 - academic.oup.com
Orally administered acetazolamide has a limited use in glaucoma due to the systemic side
effects associated with its use. No topical formulation of acetazolamide is available, mainly …
effects associated with its use. No topical formulation of acetazolamide is available, mainly …
Formulation and characterization of epalrestat-loaded polysorbate 60 cationic niosomes for ocular delivery
The aim of this work was to develop niosomes for the ocular delivery of epalrestat, a drug
that inhibits the polyol pathway and protects diabetic eyes from damage linked to sorbitol …
that inhibits the polyol pathway and protects diabetic eyes from damage linked to sorbitol …
Effects of surfactant type and cholesterol level on niosomes physical properties and in vivo ocular performance using timolol maleate as a model drug
This study aimed at investigating the roles of both Span® surfactant type (having a gel/liquid
transition temperature range from< 10 to 55° C), and cholesterol level on in vitro …
transition temperature range from< 10 to 55° C), and cholesterol level on in vitro …
Emerging potential of niosomes in ocular delivery
Introduction Niosomes have recently grabbed attention as one of the best tools for various
site-specific drug delivery systems, including ophthalmic drug delivery. Surfactants …
site-specific drug delivery systems, including ophthalmic drug delivery. Surfactants …