Biosynthesis of friedelane and quinonemethide triterpenoids is compartmentalized in Maytenus aquifolium and Salacia campestris
J Corsino, PRF de Carvalho, MJ Kato, LR Latorre… - Phytochemistry, 2000 - Elsevier
Maytenus aquifolium (Celastraceae) and Salacia campestris (Hippocrateaceae) species
accumulate friedelane and quinonemethide triterpenoids in their leaves and root bark …
accumulate friedelane and quinonemethide triterpenoids in their leaves and root bark …
Friedelin Synthase from Maytenus ilicifolia: Leucine 482 Plays an Essential Role in the Production of the Most Rearranged Pentacyclic Triterpene
TM Souza-Moreira, TB Alves, KA Pinheiro… - Scientific reports, 2016 - nature.com
Among the biologically active triterpenes, friedelin has the most-rearranged structure
produced by the oxidosqualene cyclases and is the only one containing a cetonic group. In …
produced by the oxidosqualene cyclases and is the only one containing a cetonic group. In …
CYP712K4 Catalyzes the C-29 Oxidation of Friedelin in the Maytenus ilicifolia Quinone Methide Triterpenoid Biosynthesis Pathway
KU Bicalho, MM Santoni, P Arendt… - Plant and Cell …, 2019 - academic.oup.com
Abstract The native Brazilian plant Maytenus ilicifolia accumulates a set of quinone methide
triterpenoids with important pharmacological properties, of which maytenin, pristimerin and …
triterpenoids with important pharmacological properties, of which maytenin, pristimerin and …
Functional characterization of an oxidosqualene cyclase (PdFRS) encoding a monofunctional friedelin synthase in Populus davidiana
JY Han, CH Ahn, PB Adhikari, S Kondeti, YE Choi - Planta, 2019 - Springer
Main conclusion An oxidosqualene cyclase (PdFRS) from Populus davidiana was
characterized as a monofunctional friedelin synthase by its heterologous expression in yeast …
characterized as a monofunctional friedelin synthase by its heterologous expression in yeast …
Cloning and characterization of oxidosqualene cyclases from Kalanchoe daigremontiana: enzymes catalyzing up to 10 rearrangement steps yielding friedelin and …
The first committed step in triterpenoid biosynthesis is the cyclization of oxidosqualene to
polycyclic alcohols or ketones C 30 H 50 O. It is catalyzed by single oxidosqualene cyclase …
polycyclic alcohols or ketones C 30 H 50 O. It is catalyzed by single oxidosqualene cyclase …
Biogenetically important quinonemethides and other triterpenoid constituents of Salacia reticulata
B Dhanabalasingham, V Karunaratne, Y Tezuka… - Phytochemistry, 1996 - Elsevier
Phytochemical investigation of the outer root bark of Salacia reticulata var. β-diandra
(Celastraceae) has resulted in the isolation of two novel quinonemethide triterpenoids …
(Celastraceae) has resulted in the isolation of two novel quinonemethide triterpenoids …
Effect of gypsogenin 3, O-glucuronide pretreatment of Gypsophila paniculata and Saponaria officinalis cell suspension cultures on the activities of microsomal 2, 3 …
M Henry, A Rahier, M Taton - Phytochemistry, 1992 - Elsevier
The regulation of triterpenoid saponin biosynthesis in Gypsophila paniculata and Saponaria
officinalis suspension cells has been investigated by studying the effects of adding …
officinalis suspension cells has been investigated by studying the effects of adding …
Cell cultures of Maytenus ilicifolia Mart. are richer sources of quinone-methide triterpenoids than plant roots in natura
The quinone-methide triterpenoids (QMTs) are chemotaxonomic markers of the family
Celastraceae and many compounds of this class possess important anticancer and anti …
Celastraceae and many compounds of this class possess important anticancer and anti …
Probing the functions of friedelane‐type triterpene cyclases from four celastrol‐producing plants
Y Lu, Y Luo, J Zhou, T Hu, L Tu, Y Tong, P Su… - The Plant …, 2022 - Wiley Online Library
Triterpenes are among the most diverse plant natural products, and their diversity is closely
related to various triterpene skeletons catalyzed by different 2, 3‐oxidosqualene cyclases …
related to various triterpene skeletons catalyzed by different 2, 3‐oxidosqualene cyclases …
Quantitative determination of cytotoxicFriedo‐nor‐oleanane derivatives from five morphological types of Maytenus ilicifolia (celastraceae) by reverse‐phase high …
WB Filho, J Corsino, VS Bolzani… - … Journal of Plant …, 2002 - Wiley Online Library
Five different morphological types of Maytenus ilicifolia of the same age and harvested
under the same conditions showed distinct accumulations of some friedo‐nor‐oleananes. A …
under the same conditions showed distinct accumulations of some friedo‐nor‐oleananes. A …