The objectives of this study were to investigate the immune response to intradermal
immunization with wall teichoic acid (WTA) and the effect of MBL deficiency in a murine …

Staphylococcus aureus is a Gram-positive bacterial pathogen that is decorated by
glycopolymers, including wall teichoic acid (WTA), peptidoglycan, lipoteichoic acid, and …

Wall teichoic acid (WTA) of Staphylococcus aureus is a major cell envelope-associated
glycopolymer that is a key molecule in promoting colonization during S. aureus infection …

Staphylococcus aureus is a major cause of severe nosocomial and community-acquired
infections. Phagocytes and humoral molecules, including complement, have been proposed …

Gram-positive organisms like Staphylococcus aureus are a major cause of morbidity and
mortality worldwide. Humoral response molecules together with phagocytes play a role in …

Mannose-binding lectin (MBL), a pattern recognition innate immune molecule, selectively
binds distinct chemical patterns, including carbohydrates expressed on Group B …

Innate immunity is the first line of host defense against invading pathogens, and it is
recognized by a variety of pattern recognition molecules, including mannose-binding lectin …

The innate immune system is evolutionarily ancient and biologically primitive. Historically, it
was first identified as an element of the immune system that provides the first-line response …

Staphylococcus aureus is a Gram-positive pathogen that can cause chronic skin
inflammation, pneumonia, and septic shock. The immunomodulatory functions of wall …

Innate immunity is the earliest response to invading microbes and acts to contain infection in
the first minutes to hours of challenge. Unlike adaptive immunity that relies upon clonal …