Background Despite the increased risk of cardiovascular disease and type 2 diabetes
associated with excess bodyweight, development of a clinically meaningful metric for health …

Background Data are scarce for the lifetime risk of developing impaired glucose metabolism,
including prediabetes, as are data for the risk of eventual progression from prediabetes to …

Krishnan Bhaskaran and colleagues1 found a J-shaped association between BMI and
overall mortality among 3· 6 million adults in the UK. This study provides further support for …

Background BMI is known to be strongly associated with all-cause mortality, but few studies
have been large enough to reliably examine associations between BMI and a …

Background Diabetes is a major public health issue. Because lifetime risk, life expectancy,
and years of life lost are meaningful metrics for clinical decision making, we aimed to …

Rising prevalence of obesity is a worldwide health concern because excess weight gain
within populations forecasts an increased burden from several diseases, most notably …

Background Targeted obesity prevention policies would benefit from the identification of
population groups with the highest risk of weight gain. The relative importance of adult age …

OBJECTIVE—We assessed the lifetime risk of cardiovascular disease (CVD) among
individuals with and without obesity and diabetes. RESEARCH DESIGN AND METHODS …

Background The prevalence of type 2 diabetes is increasing rapidly, particularly among
younger age groups. Estimates suggest that people with diabetes die, on average, 6 years …

Background Diabetes incidence has increased and mortality has decreased greatly in the
USA, potentially leading to substantial changes in the lifetime risk of diabetes. We aimed to …