Varied doses and chemical forms of selenium supplementation differentially affect mouse intestinal physiology

Q Zhai, Y Xiao, P Li, F Tian, J Zhao, H Zhang… - Food & function, 2019 - pubs.rsc.org
In this study, the effects of three doses (diets containing< 0.01, 0.15, 0.40 mg kg− 1 Se) and
two forms (sodium selenite and selenomethionine) of dietary Se supplementation on the …

Effects of dietary selenium supplementation on intestinal barrier and immune responses associated with its modulation of gut microbiota

Q Zhai, S Cen, P Li, F Tian, J Zhao… - … & Technology Letters, 2018 - ACS Publications
Variations in selenium (Se) intake have been reported to affect the barrier function and
immune responses in the gut. Previous studies mainly focused on the role of Se itself or its …

Selenium and selenoproteins in inflammatory bowel diseases and experimental colitis

B Speckmann, H Steinbrenner - Inflammatory bowel diseases, 2014 - academic.oup.com
Inadequate dietary intake of the essential trace element selenium (Se) is thought to be a risk
factor for several chronic diseases associated with oxidative stress and inflammation …

Effect of gut microflora on nutritional availability of selenium

K Takahashi, N Suzuki, Y Ogra - Food chemistry, 2020 - Elsevier
Since selenium (Se) is an essential mineral, animals must be able to metabolize the various
selenocompounds in meat, fish and vegetables. It is unclear how animals, including …

[HTML][HTML] Selenium in human health and gut microflora: bioavailability of selenocompounds and relationship with diseases

RLU Ferreira, KCM Sena-Evangelista… - Frontiers in …, 2021 - frontiersin.org
This review covers current knowledge of selenium in the dietary intake, its bioavailability,
metabolism, functions, biomarkers, supplementation and toxicity, as well as its relationship …

In vitro digestion and fecal fermentation of selenocompounds: impact on gut microbiota, antioxidant activity, and short-chain fatty acids

S Liang, J Yu, M Zhao, S Chen, X Lu, F Ye… - Food Research …, 2024 - Elsevier
Selenium bioavailability is critically influenced by gut microbiota, yet the interaction
dynamics with selenocompounds remain unexplored. Our study found that L …

Chemical form of selenium affects its uptake, transport, and glutathione peroxidase activity in the human intestinal Caco-2 cell model

H Zeng, MI Jackson, WH Cheng, GF Combs - Biological trace element …, 2011 - Springer
Determining the effect of selenium (Se) chemical form on uptake, transport, and glutathione
peroxidase activity in human intestinal cells is critical to assess Se bioavailability at …

[HTML][HTML] Review on the health-promoting effect of adequate selenium status

Y Sun, Z Wang, P Gong, W Yao, Q Ba, H Wang - Frontiers in Nutrition, 2023 - frontiersin.org
Selenium is an essential microelement involved in various biological processes. Selenium
deficiency increases the risk of human immunodeficiency virus infection, cancer …

[HTML][HTML] Gene expression profiling of low selenium status in the mouse intestine: transcriptional activation of genes linked to DNA damage, cell cycle control and …

L Rao, TA Prolla, B Puschner - The Journal of nutrition, 2001 - Elsevier
The essential trace mineral selenium (Se) has been shown previously to inhibit intestinal,
prostate, lung and liver tumor development and associated mortality in both experimental …

Biotransformation of l-Selenomethionine and Selenite in Rat Gut Contents

W Krittaphol, A McDowell, CD Thomson… - Biological trace element …, 2011 - Springer
Abstract l-Selenomethionine (SeMet) and sodium selenite are widely used selenium
nutritional supplements with potential benefit in preventing cancer. However …