Background: Although in vitro studies and investigations in animal models and small clinical
populations have suggested that ceramides may represent an intermediate link between …

Several studies indicated how dietary patterns that were obtained from nutritional cluster
analysis can predict disease risk or mortality. Low-grade chronic inflammation represents a …

Background Recent cohort studies evaluated the association between some previously
identified high-risk ceramides [Cer (d18: 1/16: 0), Cer (d18: 1/18: 0), Cer (d18: 1/22: 0), Cer …

Objective—Ceramides are molecular lipids implicated in apoptosis, inflammation, obesity,
and insulin resistance. An earlier study reported that ceramides were associated with fatal …

Background Recent studies suggest that circulating concentrations of specific ceramide
species may be associated with coronary risk and mortality. We sought to determine the …

Aims/hypothesis Ceramide lipids have a role in the development of insulin resistance,
diabetes and risk of cardiovascular disease. Here we investigated four ceramides and their …

Objective—Ceramides are sphingolipids involved with cellular signaling. Synthesis of
ceramides occurs in all tissues. Ceramides accumulate within tissues and the blood plasma …

Ceramides are bioactive lipids that have an important role in many cellular functions such as
apoptosis and inflammation. During the past decade emerging clinical data have shown that …

Background: Few studies have assessed the associations of ceramides and sphingomyelins
(SMs) with diabetes in humans. Objective: We assessed associations of 15 circulating …

Metabolic alterations precede cardiometabolic disease onset. Here we present ceramide-
and dihydroceramide-profiling data from a nested case-cohort (type 2 diabetes [T2D, n …