Pulmonary perfusion heterogeneity is increased by sustained, heavy exercise in humans

KJ Burnham, TJ Arai, DJ Dubowitz… - Journal of Applied …, 2009 - journals.physiology.org
Exercise presents a considerable stress to the pulmonary system and ventilation-perfusion
(V̇a/Q̇) heterogeneity increases with exercise, affecting the efficiency of gas exchange. In …

The heterogeneity of regional specific ventilation is unchanged following heavy exercise in athletes

V Tedjasaputra, RC Sá, TJ Arai… - Journal of applied …, 2013 - journals.physiology.org
Heavy exercise increases ventilation-perfusion mismatch and decreases pulmonary gas
exchange efficiency. Previous work using magnetic resonance imaging (MRI) arterial spin …

VA/Q distribution during heavy exercise and recovery in humans: implications for pulmonary edema

W Schaffartzik, DC Poole, T Derion… - Journal of Applied …, 1992 - journals.physiology.org
Ventilation-perfusion (VA/Q) inequality has been shown to increase with exercise. Potential
mechanisms for this increase include nonuniform pulmonary vasoconstriction, ventilatory …

Effect of prolonged, heavy exercise on pulmonary gas exchange in athletes

SR Hopkins, TP Gavin, NM Siafakas… - Journal of Applied …, 1998 - journals.physiology.org
During maximal exercise, ventilation-perfusion inequality increases, especially in athletes.
The mechanism remains speculative. We hypothesized that, if interstitial pulmonary edema …

Human lung density is not altered following normoxic and hypoxic moderate-intensity exercise: implications for transient edema

ANH Hodges, AW Sheel, JR Mayo… - Journal of Applied …, 2007 - journals.physiology.org
The purpose of this study was to examine the effects of exercise on extravascular lung water
as it may relate to pulmonary gas exchange. Ten male humans underwent measures of …

Regional pulmonary blood flow during rest, tilt, and exercise in unanesthetized dogs

JC Parker, JL Ardell, CR Hamm… - Journal of Applied …, 1995 - journals.physiology.org
We assessed the heterogeneity of regional pulmonary blood flow (PBFr), using radioactive
microspheres in five unanesthetized dogs standing at rest (Rest), standing at a 45 degrees …

Pulmonary vascular distensibility predicts aerobic capacity in healthy individuals

S Lalande, P Yerly, V Faoro… - The Journal of physiology, 2012 - Wiley Online Library
Key points Pulmonary transit of agitated contrast (PTAC) occurs during exercise in healthy
individuals. It has been suggested that positive PTAC reflects a greater pulmonary vascular …

Distribution of lung density after strenuous, prolonged exercise

G Manier, M Duclos, L Arsac… - Journal of Applied …, 1999 - journals.physiology.org
The postexercise alteration in pulmonary gas exchange in high-aerobically trained subjects
depends on both the intensity and the duration of exercise (G. Manier, J. Moinard, and H …

Ventilation-perfusion inequality in normal humans during exercise at sea level and simulated altitude

GE Gale, JR Torre-Bueno, RE Moon… - Journal of Applied …, 1985 - journals.physiology.org
To investigate the effects of both exercise and acute exposure to high altitude on ventilation-
perfusion (VA/Q) relationships in the lungs, nine young men were studied at rest and at up to …

Pulmonary interstitial edema in the pig after heavy exercise

W Schaffartzik, J Arcos, K Tsukimoto… - Journal of Applied …, 1993 - journals.physiology.org
During exercise (especially in hypoxia), the alveolar-arterial O2 tension difference
increases. This impairment of pulmonary gas exchange is caused partly by diffusion …