Type 1 diabetes mellitus (T1DM) is one of the T-cell mediated autoimmune diseases and
vitamin D suppresses activation of T-cell and has immunomodulatory effects. In this study …

Background Type 1 diabetes mellitus (T1DM) is recognized as a T-cell-mediated
autoimmune disease. Vitamin D compounds are known to suppress T-cell activation by …

Background Diabetes mellitus is a condition with a defect in insulin secretion and insulin
function. Some of the vitamin D receptor gene polymorphisms related to increasing the …

INTRODUCTION: Association studies of vitamin D receptor (VDR) polymorphisms and risk of
type 1 diabetes (T1D) have produced inconsistent results in different populations, pointing to …

BACKGROUND AND AIMS: A number of studies have shown that polymorphisms in the
vitamin D receptor (VDR) gene are implicated in susceptibility to type 2 diabetes (T2D) …

Background: Type 1 diabetes mellitus (TIDM) results from an immune-mediated destruction
of insulin-producing-cells in the pancreatic islets of Langerhans. There are clear differences …

Background The incidence of type 1 diabetes mellitus (T1DM) in Kuwait is amongst the
highest in the world. Vitamin D is considered to be involved in immune modulation and its …

Methods: A total of 439 unrelated patients with T2DM and 302 healthy controls were
included in the study. Genomic DNA was extracted from blood and genotyped for the single …

Many cellular, preclinical and observational studies support a role of vitamin D in
pathogenesis of type-1 diabetes mellitus (DM). The vitamin D receptor (VDR) locus has …

Type 1 diabetes mellitus (T1DM) is a T cell mediated autoimmune disease. Vitamin D was
found to suppress the incidence of diabetes when bind to its receptor (VDR), probably by …