Thymic stromal lymphopoietin-mediated STAT5 phosphorylation via kinases JAK1 and JAK2 reveals a key difference from IL-7–induced signaling
Y Rochman, M Kashyap… - Proceedings of the …, 2010 - National Acad Sciences
Thymic stromal lymphopoietin (TSLP) is a type I cytokine that plays essential roles in
allergic/inflammatory skin and airway disorders, in helminth infections, and in regulating …
allergic/inflammatory skin and airway disorders, in helminth infections, and in regulating …
Requirement for stat5 in thymic stromal lymphopoietin-mediated signal transduction
DE Isaksen, H Baumann, PA Trobridge… - The Journal of …, 1999 - journals.aai.org
Thymic stromal lymphopoietin (TSLP) is a newly identified cytokine that uniquely promotes B
lymphopoiesis to the B220+/IgM+ immature B cell stage. In addition, TSLP shares many …
lymphopoiesis to the B220+/IgM+ immature B cell stage. In addition, TSLP shares many …
Uncoupling of proliferation and Stat5 activation in thymic stromal lymphopoietin-mediated signal transduction
DE Isaksen, H Baumann, B Zhou, S Nivollet… - The Journal of …, 2002 - journals.aai.org
Thymic stromal lymphopoietin (TSLP) is a cytokine that facilitates B lymphocyte
differentiation and costimulates T cells. Previous studies have demonstrated that a functional …
differentiation and costimulates T cells. Previous studies have demonstrated that a functional …
Thymic stromal lymphopoietin: a cytokine that promotes the development of IgM+ B cells in vitro and signals via a novel mechanism
SD Levin, RM Koelling, SL Friend… - The Journal of …, 1999 - journals.aai.org
A novel cytokine from a thymic stromal cell line (thymic stromal lymphopoietin (TSLP))
promotes the development of B220+/IgM+ immature B cells when added to fetal liver …
promotes the development of B220+/IgM+ immature B cells when added to fetal liver …
Thymic stromal lymphopoietin
R He, RS Geha - Annals of the New York Academy of Sciences, 2010 - Wiley Online Library
Thymic stromal lymphopoietin (TSLP) is an epithelial cell‐derived cytokine expressed in
skin, gut, lungs, and thymus. TSLP signals via a TSLP receptor (TSLPR), a heterodimer of …
skin, gut, lungs, and thymus. TSLP signals via a TSLP receptor (TSLPR), a heterodimer of …
Thymic stromal lymphopoietin drives the development of IL-13+ Th2 cells
S Ochiai, F Jagot, RL Kyle, E Hyde… - Proceedings of the …, 2018 - National Acad Sciences
T helper 2 (Th2) cells are pivotal in the development of allergy. Allergen exposure primes IL-
4+ Th2 cells in lymph node, but production of effector cytokines including IL-5 and IL-13 is …
4+ Th2 cells in lymph node, but production of effector cytokines including IL-5 and IL-13 is …
TSLP and IL-7 use two different mechanisms to regulate human CD4+ T cell homeostasis
N Lu, YH Wang, YH Wang, K Arima… - Journal of Experimental …, 2009 - rupress.org
Whether thymic stromal lymphopoietin (TSLP) directly induces potent human CD4+ T cell
proliferation and Th2 differentiation is unknown. We report that resting and activated CD4+ T …
proliferation and Th2 differentiation is unknown. We report that resting and activated CD4+ T …
The role of thymic stromal lymphopoietin in CD8+ T cell homeostasis
Y Rochman, WJ Leonard - The Journal of Immunology, 2008 - journals.aai.org
Thymic stromal lymphopoietin (TSLP) is a cytokine produced by stromal cells, epithelial
cells, and basophils that acts on dendritic cells, mast cells, and CD4+ T cells. The receptor …
cells, and basophils that acts on dendritic cells, mast cells, and CD4+ T cells. The receptor …
Functions of thymic stromal lymphopoietin in immunity and disease
Y Zhang, B Zhou - Immunologic research, 2012 - Springer
Thymic stromal lymphopoietin (TSLP) is an interleukin 7-like cytokine expressed mainly by
epithelial cells. Current studies provide compelling evidence that TSLP is capable of …
epithelial cells. Current studies provide compelling evidence that TSLP is capable of …
Induction of IL-4 expression in CD4+ T cells by thymic stromal lymphopoietin
M Omori, S Ziegler - The Journal of Immunology, 2007 - journals.aai.org
The cytokine thymic stromal lymphopoietin (TSLP) has been implicated in the development
and progression of allergic inflammation in both humans and mice. Although the underlying …
and progression of allergic inflammation in both humans and mice. Although the underlying …