Serum uric acid may be an independent risk factor for cardiovascular disease. This review
examines this association, potential mechanisms, and explores whether strategies to reduce …

Uric acid is the end-product of purine catabolism. Hyperuricaemia is implicated in disorders
such as gout and urolithiasis and recent epidemiological evidence suggests an association …

There is a now a wealth of epidemiological, animal, and clinical data to suggest the benefits
of uric acid reduction and hxanthine oxidase inhibition in prevention of vascular disease …

SUMMARY A substantial body of epidemiological and experimental evidence suggests that
serum uric acid is an important, independent risk factor for cardiovascular and renal disease …

Recent evidence would indicate that high serum uric acid (SUA) levels can be a significant
and independent risk factor for hypertension and cardiovascular diseases, such as ischemic …

Many studies have shown a strong correlation between urate levels and cardiovascular
disease. The formation of urate is complex as the same enzyme that produces urate …

The association between increased uric acid (UA) levels and cardiovascular disease (CVD)
has been observed and studied for many decades. The value of UA as an independent …

Borghi and Desideri Allopurinol and Cardiovascular Disease 497 the increase in the
endothelium-dependent forearm vasodilatation was enhanced by allopurinol in a dose …

Uric acid (UA) is the final end product of purine catabolism and is formed from xanthines and
hypoxanthines. Hyperuricemia can be secondary to either an exaggerated production of UA …

Over recent years there has been renewed debate about the nature of the association
between raised serum uric acid concentration and cardiovascular disease. 1 Several large …