In recent years there has been an increasing appreciation that microbial biofilms are
ubiquitous, which has resulted in a number of studies on infectious diseases from a biofilm …

Our classical perception of microorganisms as unicellular life forms is almost entirely based
on the pure-culture mode of growth; since microbial suspensions can be diluted to a single …

Candida albicans, C. glabrata, C. parapsilosis, and C. tropicalis are able to form biofilms on
virtually any biomaterial implanted in a human host. Biofilms are a primary cause of mortality …

Little is known about fungal biofilms, which may cause infection and antibiotic resistance. In
this study, biofilm formation by different Candida species, particularly Candida albicans and …

Device-associated microbial growth, including Candida biofilms, represents more than half
of all human microbial infections and, despite a relatively small risk of implant-associated …

The use of indwelling devices in current therapeutic practice is associated with hospital‐
acquired bloodstream and deep tissue infections (1). Transplantation medical procedures …

Many Candida infections involve biofilm formation on implanted devices such as an
indwelling catheter, a prosthetic heart valve or a denture. Candida biofilms can be formed in …

In healthcare settings, Candida spp. cause invasive disease with high mortality. The
overwhelming majority of cases are associated with the use of critically-needed medical …

Pathogenic fungi in the genus Candida can cause both superficial and serious systemic
disease, and are now recognized as major agents of hospital-acquired infection. Many …

Biofilms, likely the predominant mode of device-related microbial infection, exhibit resistance
to antimicrobial agents. Evidence suggests that Candida biofilms have dramatically reduced …