Childbirth and consequent atopic disease: emerging evidence on epigenetic effects based on the hygiene and EPIIC hypotheses

HG Dahlen, S Downe, ML Wright, HP Kennedy… - BMC pregnancy and …, 2016 - Springer
Background In most high and middle income countries across the world, at least 1: 4 women
give birth by cesarean section. Rates of labour induction and augmentation are rising …

Gut microbiota and allergy: the importance of the pregnancy period

TR Abrahamsson, RY Wu, MC Jenmalm - Pediatric research, 2015 - nature.com
Limited microbial exposure is suggested to underlie the increase of allergic diseases in
affluent countries, and bacterial diversity seems to be more important than specific bacteria …

Atopic dermatitis and pregnancy

G Balakirski, N Novak - Journal of Allergy and Clinical Immunology, 2022 - Elsevier
Fascinating immunologic mechanisms that are crucial for pregnancy can, however, lead to
the development of different skin conditions, of which atopic dermatitis (AD) is the most …

Childhood immune maturation and allergy development: regulation by maternal immunity and microbial exposure

MC Jenmalm - American journal of reproductive immunology, 2011 - Wiley Online Library
Citation Jenmalm MC. Childhood Immune Maturation and Allergy Development: Regulation
by Maternal Immunity and Microbial Exposure. Am J Reprod Immunol 2011; 66 (Suppl. 1) …

Atopic dermatitis in pregnancy: current status and challenges

I Koutroulis, J Papoutsis… - … & gynecological survey, 2011 - journals.lww.com
Atopic dermatitis (AD) is the most common pregnancy dermatosis. This evidence-based
review article provides an evaluation of AD in gestation. Our literature search revealed 4 …

The maternal microbiome during pregnancy and allergic disease in the offspring

PJ Vuillermin, L Macia, R Nanan, MLK Tang… - Seminars in …, 2017 - Springer
There is substantial epidemiological and mechanistic evidence that the increase in allergic
disease and asthma in many parts of the world in part relates to changes in microbial …

Hygiene hypothesis and autoimmune diseases

GAW Rook - Clinical reviews in allergy & immunology, 2012 - Springer
Throughout the twentieth century, there were striking increases in the incidences of many
chronic inflammatory disorders in the rich developed countries. These included autoimmune …

The immune system and microbiome in pregnancy

GM Fuhler - Best Practice & Research Clinical Gastroenterology, 2020 - Elsevier
Hormonal changes during pregnancy instigate numerous physiological changes aimed at
the growth and delivery of a healthy baby. A careful balance between immunological …

Prenatal depression, breastfeeding, and infant gut microbiota

N Rodriguez, HM Tun, CJ Field, PJ Mandhane… - Frontiers in …, 2021 - frontiersin.org
Depressive symptoms are common during pregnancy and are estimated to affect 7–20% of
pregnant women, with higher prevalence found in those with a prior history of depression, in …

Could peripartum antibiotics have delayed health consequences for the infant?

AR Bedford Russell, SH Murch - BJOG: An International …, 2006 - Wiley Online Library
Antibiotics are increasingly prescribed in the peripartum period, for both maternal and fetal
indications. Their effective use undoubtedly reduces the incidence of specific invasive …