We describe the landscape of somatic genomic alterations based on multidimensional and
comprehensive characterization of more than 500 glioblastoma tumors (GBMs). We identify …

Summary The Cancer Genome Atlas Network recently cataloged recurrent genomic
abnormalities in glioblastoma multiforme (GBM). We describe a robust gene expression …

Diverse genetic, epigenetic, and developmental programs drive glioblastoma, an incurable
and poorly understood tumor, but their precise characterization remains challenging. Here …

During the last decade, extensive multiplatform genome‐wide analysis has yielded a wealth
of knowledge regarding the genetic and molecular makeup of glioblastoma multiforme …

Background Glioblastoma multiforme (GBM) is an umbrella designation that includes a
heterogeneous group of primary brain tumors. Several classification strategies of GBM have …

The identification of distinct genetic and epigenetic profiles in different types of gliomas has
revealed novel diagnostic, prognostic, and predictive molecular biomarkers for refinement of …

Genome-wide molecular-profiling studies have revealed the characteristic genetic
alterations and epigenetic profiles associated with different types of gliomas. These …

Glioblastoma multiforme (GBM) is an aggressive and lethal cancer, accounting for the
majority of primary brain tumors in adults. GBMs are characterized by genetic alterations …

In recent years, important advances have been achieved in the understanding of the
molecular biology of glioblastoma multiforme (GBM); thus, complex genetic alterations and …

Primary brain tumors are a leading cause of cancer-related mortality among young adults
and children. The most common primary malignant brain tumor, glioma, carries a median …