Abstract Learning Objectives After completing this course, the reader will be able to:
Describe the site-specific dysregulation of some miRNAs and explain their potential as non …

Background To date, there are no highly sensitive and specific minimally invasive
biomarkers for detection of breast cancer at an early stage. The occurrence of circulating …

Purpose: There is a quest for novel noninvasive diagnostic markers for the detection of
breast cancer. The goal of this study is to identify circulating microRNA (miRNA) signatures …

Background We previously showed microRNAs (miRNAs) in plasma are potential
biomarkers for colorectal cancer detection. Here, we aimed to develop specific blood-based …

Introduction MicroRNAs (miRNAs) are a group of small noncoding RNAs involved in the
regulation of gene expression. As such, they regulate a large number of cellular pathways …

BACKGROUND The identification of novel biomarkers for early breast cancer detection
would be a great advance. Because of their role in tumorigenesis and stability in body fluids …

MicroRNAs (miRNAs) are a new class of short noncoding regulatory RNAs (18–25
nucleotides) that are involved in diverse developmental and pathologic processes. Altered …

Objective: The development of clinically validated biomarkers for cancer has remained an
insurmountable task despite other advances in the field of cancer molecular biology. Mi (cro) …

Introduction There are currently no highly sensitive and specific minimally invasive
biomarkers for detection of early-stage breast cancer. MicroRNAs (miRNAs) are present in …

MicroRNA (miRNA or miR) is stably present in plasma. It has been reported that miRNA
could be used for detecting cancer. Circulating miRNAs are being increasingly recognized …