A multitude of cell screening assays for diagnostic and research applications rely on
quantitative measurements of a sample in the presence of different reagent concentrations …

Microfluidic live cell arrays with integrated concentration gradient or mixture generators have
been utilized in screening cellular responses to various biomolecular cues. Microfluidic …

Cell culture is typically performed in Petri dishes, with a few million cells growing together, or
in microwell plates with thousands of cells in each compartment. When the throughput of …

Studying the potency of small-molecules on eukaryotic and prokaryotic cells using
conventional biological settings requires time-consuming procedures and large volumes of …

Here, we report the fabrication of a chemical gradient microfluidic device for single-cell
cytotoxicity assays. This device consists of a microfluidic chemical gradient generator and a …

Here, we develop an injection molded microfluidic approach for single cell analysis by
making use of (1) rapidly curing injectable hydrogels,(2) a high density microfluidic weir trap …

A microfluidic diffusion diluter to create stable chemical gradients across an array of cell
cultures was demonstrated. The device enabled concentration based studies to be …

High-throughput screening (HTS) is a method of scientific experimentation widely used in
drug discovery and relevant to the fields of biology and chemistry. Microfluidic systems …

Microscale techniques have been applied to biological assays for nearly two decades, but
haven't been widely integrated as common tools in biological laboratories. The significant …

High-throughput screening (HTS) is a method of scientific experimentation widely used in
drug discovery and relevant to the fields of biology. The development of micro-and …