Anti-inflammatory therapy for atherosclerosis: focusing on cytokines

AV Poznyak, D Bharadwaj, G Prasad… - International journal of …, 2021 - mdpi.com
Atherosclerosis is a well-known global health problem. Despite the high prevalence of the
disease, numerous aspects of pathogenesis remain unclear. Subsequently, there are still no …

Cytokines: roles in atherosclerosis disease progression and potential therapeutic targets

JWE Moss, DP Ramji - Future medicinal chemistry, 2016 - Future Science
Atherosclerosis, the primary cause of cardiovascular disease (CVD), is a chronic
inflammatory disorder in the walls of medium and large arteries. CVD is currently …

Potential of anti-inflammatory agents for treatment of atherosclerosis

DA Chistiakov, AA Melnichenko, AV Grechko… - … and molecular pathology, 2018 - Elsevier
Chronic inflammation is a central pathogenic mechanism of atherosclerosis induction and
progression. Vascular inflammation is associated with accelerated onset of late …

Inflammation: a novel therapeutic target/direction in atherosclerosis

B Li, W Li, X Li, H Zhou - Current Pharmaceutical Design, 2017 - ingentaconnect.com
Over the past two decades, the viewpoint of atherosclerosis has been replaced gradually by
a lipiddriven, chronic, low-grade inflammatory disease of the arterial wall. Current treatment …

Systemic inflammatory response and atherosclerosis: the paradigm of chronic inflammatory rheumatic diseases

A Arida, AD Protogerou, GD Kitas… - International journal of …, 2018 - mdpi.com
Patients with Chronic Inflammatory Rheumatic diseases (CIRD) are at increased risk of
cardiovascular disease (CVD), ascribed not only to classical risk factors, but also to the …

Anti-inflammatory therapeutics for the treatment of atherosclerosis

IF Charo, R Taub - Nature reviews Drug discovery, 2011 - nature.com
Atherosclerosis is the primary cause of heart disease and stroke and is thus the underlying
pathology of the leading causes of death in the western world. Although risk can be reduced …

Role of inflammatory cytokines in genesis and treatment of atherosclerosis

E Biros, JE Reznik, CS Moran - Trends in Cardiovascular Medicine, 2022 - Elsevier
Atherosclerosis demonstrates an increased rate of vascular smooth muscle cells (VSMC)
plasticity characterized by switching from the differentiated contractile phenotype to a de …

Inflammatory cytokines in atherosclerosis: current therapeutic approaches

D Tousoulis, E Oikonomou, EK Economou… - European heart …, 2016 - academic.oup.com
The notion of atherosclerosis as a chronic inflammatory disease has intensified research on
the role of cytokines and the way these molecules act and interact to initiate and sustain …

[HTML][HTML] Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets

DP Ramji, TS Davies - Cytokine & growth factor reviews, 2015 - Elsevier
Atherosclerosis, a chronic inflammatory disorder of the arteries, is responsible for most
deaths in westernized societies with numbers increasing at a marked rate in developing …

[HTML][HTML] Anti-inflammatory therapy for cardiovascular disease

CE Kosmas, D Silverio, A Sourlas… - Annals of …, 2019 - ncbi.nlm.nih.gov
Chronic subclinical inflammation is a central process in the pathogenesis of cardiovascular
disease (CVD) and it has been linked with both the initiation and progression of …