β-Lapachone inhibits lung metastasis of colorectal cancer by inducing apoptosis of CT26 cells
Background: β-Lapachone is a quinone-containing compound found in red lapacho
(Tabebuia impetiginosa, syn. T avellanedae) trees. Lapacho has been used in traditional …
(Tabebuia impetiginosa, syn. T avellanedae) trees. Lapacho has been used in traditional …
β-Lapachone suppresses the lung metastasis of melanoma via the MAPK signaling pathway
β-Lapachone is a natural quinone compound from Lapacho trees, which has various
pharmacological effects such as anti-bacterial, anti-fungal, anti-viral, and anti-inflammatory …
pharmacological effects such as anti-bacterial, anti-fungal, anti-viral, and anti-inflammatory …
β-Lapachone Induces Cell Cycle Arrest and Apoptosis in Human Colon Cancer Cells
L Huang, AB Pardee - Molecular Medicine, 1999 - Springer
Background Human colon cancers have a high frequency of p53 mutations, and cancer cells
expressing mutant p53 tend to be resistant to current chemo-and radiation therapy. It is thus …
expressing mutant p53 tend to be resistant to current chemo-and radiation therapy. It is thus …
[HTML][HTML] Anticancer Potential and Safety Profile of β-Lapachone In Vitro
KMM Lima, LF Calandrini de Azevedo, JD Rissino… - Molecules, 2024 - mdpi.com
Ipê is a plant of the Bignoniaceae family. Among the compounds extracted from this tree,
lapachol is notable because its structural modification allows the production of β-lapachone …
lapachol is notable because its structural modification allows the production of β-lapachone …
β-Lapachone-induced apoptosis is associated with activation of caspase-3 and inactivation of NF-κB in human colon cancer HCT-116 cells
BT Choi, JH Cheong, YH Choi - Anti-cancer drugs, 2003 - journals.lww.com
Abstract β-Lapachone is a naturally occurring quinone obtained from the bark of the lapacho
tree (Tabebuia avellanedae) with cancer chemopreventive properties. The objective of the …
tree (Tabebuia avellanedae) with cancer chemopreventive properties. The objective of the …
Growth inhibition of A549 human lung carcinoma cells by β-lapachone through induction of apoptosis and inhibition of telomerase activity
HJ Woo, YH Choi - International journal of oncology, 2005 - spandidos-publications.com
The objective of the present study was to investigate the effect of β-lapachone, a quinone
obtained from the bark of the lapacho tree (Tabebuia avellanedae), on the cell growth and …
obtained from the bark of the lapacho tree (Tabebuia avellanedae), on the cell growth and …
[HTML][HTML] Inhibition of nasopharyngeal carcinoma by beta-lapachone occurs by targeting the mammalian target of rapamycin (mTOR)/PI3K/AKT pathway, reactive …
Y Han, D Shi, J Li - … Medical Journal of Experimental and Clinical …, 2019 - ncbi.nlm.nih.gov
Background Beta-lapachone has been shown to exhibit potent anti-cancer effects against
various cell lines. In the present study, we examined the anti-cancer effects of beta …
various cell lines. In the present study, we examined the anti-cancer effects of beta …
[HTML][HTML] Downregulation of Sp1 is involved in β-lapachone-induced cell cycle arrest and apoptosis in oral squamous cell carcinoma
YJ Jeon, W Bang, JC Shin… - International …, 2015 - spandidos-publications.com
Abstract β-lapachone (β-lap) is a naturally occurring quinone obtained from the bark of
lapacho tree (Tabebuia avellanedae) with anti-proliferative properties against various …
lapacho tree (Tabebuia avellanedae) with anti-proliferative properties against various …
β-lapachone suppresses the proliferation of human malignant melanoma cells by targeting specificity protein 1
W Bang, YJ Jeon, JH Cho, RH Lee… - Oncology …, 2016 - spandidos-publications.com
Abstract β-lapachone (β-lap), a novel natural quinone derived from the bark of the Pink
trumpet tree (Tabebuia avellanedae) has been demonstrated to have anticancer activity. In …
trumpet tree (Tabebuia avellanedae) has been demonstrated to have anticancer activity. In …
Demonstration of the lapachol as a potential drug for reducing cancer metastasis
IT Balassiano, SA De Paulo, NH Silva… - Oncology …, 2005 - spandidos-publications.com
Metastasis is the major process responsible for the death in cancer patients. In the search for
more effective antineoplasic drugs, many substances are under investigation, among them …
more effective antineoplasic drugs, many substances are under investigation, among them …
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