In the version of this article initially published, in Fig. 5a, the flow cytometry plot that is
second from the right in the bottom row (+ LPS,+ TGF-β+ APRIL,+ αCD40; NIKKO mice) did …

Immunoglobulin class switching is crucial for the generation of antibody diversity in humoral
immunity and, when deregulated, also has severe pathological consequences. How the …

T cell activation involves the orchestration of several signaling pathways, including that of
the'classical'transcription factor NF-κB components NF-κB1–RelA. The function of …

TBK1 suppression of IgA in the NIK of time | Nature Immunology Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

Nature Immunology Jiang et al. elucidate this pathway almost from start to finish1. NK cells
lyse target cells via spontaneous or antibody-dependent cytotoxicity (ADCC). In both cases …

IgE. In the Journal of Experimental Medicine, Lim et al. find that glucocorticoids, steroid
stress hormones that can be used as immunosuppressive drugs, induce B cells to undergo …

To investigate the importance of proteolysis of NF-κB1 p105 induced by the kinase IKK in
activation of the transcription factor NF-κB, we generated'Nfkb1 SSAA/SSAA'mice, in which …

The kinase IKKα has a well-described activating role in the noncanonical transcription factor
NF-κB pathway. Evidence now suggests that IKKα also inhibits the canonical NF-κB pathway …

Ozes et al. reply Delhase et al. take issue with our claim that Akt induces activation of NF-κB
by phosphorylating IKKα, contending that IKKα plays no role in the activation by TNF of NF …

IgE. In the Journal of Experimental Medicine, Lim et al. find that glucocorticoids, steroid
stress hormones that can be used as immunosuppressive drugs, induce B cells to undergo …