The development of type II diabetes was shown to be associated with the formation of
amyloid fibrils consisted of the islet amyloid polypeptide (IAPP or amylin). Recently, a short …

Cats and humans, unlike most rodent species, develop amyloid in the islets of Langerhans
in conjunction with non-insulin-dependent diabetes mellitus. The amyloid consists of a 37 …

Islet amyloid polypeptide (IAPP) is a 37-residue polypeptide hormone that is responsible for
islet amyloid formation in type II diabetes. Human IAPP is extremely amyloidogenic, while rat …

The aggregation of the 37‐amino acid polypeptide human islet amyloid polypeptide (hIAPP),
as either insoluble amyloid or as small oligomers, appears to play a direct role in the death …

Islet amyloid polypeptide (IAPP), a putative polypeptide hormone, is a product of pancreatic
beta-cells and the major constituent of the amyloid deposits seen mainly in islets of type 2 …

Native human islet amyloid polypeptide (hIAPP) has been identified as the major component
of amyloid plaques found in the pancreatic islets of Langerhans of persons affected by type …

The 37-residue islet amyloid polypeptide (IAPP) is the major protein component of the
amyloid deposits found in type-II diabetes. IAPP is stored in a relatively low pH environment …

Islet amyloid polypeptide (IAPP; amylin) is responsible for amyloid formation in type-2
diabetes. Not all organisms form islet amyloid, and amyloid formation correlates strongly …

Amyloid formation has been implicated in a wide range of human diseases, and a diverse
set of proteins is involved. There is considerable interest in elucidating the interactions …

Aromatic–aromatic and aromatic–hydrophobic interactions have been proposed to play a
role in amyloid formation by a range of polypeptides, including islet amyloid polypeptide …