Vertical distribution of specific ventilation in normal supine humans measured by oxygen-enhanced proton MRI

RC Sá, MV Cronin… - Journal of applied …, 2010 - journals.physiology.org
Specific ventilation (SV) is the ratio of fresh gas entering a lung region divided by its end-
expiratory volume. To quantify the vertical (gravitationally dependent) gradient of SV in eight …

Validating the distribution of specific ventilation in healthy humans measured using proton MR imaging

RC Sá, AK Asadi, RJ Theilmann… - Journal of Applied …, 2014 - journals.physiology.org
Specific ventilation imaging (SVI) uses proton MRI to quantitatively map the distribution of
specific ventilation (SV) in the human lung, using inhaled oxygen as a contrast agent. To …

Measurement of the distribution of ventilation-perfusion ratios in the human lung with proton MRI: comparison with the multiple inert-gas elimination technique

RC Sá, AC Henderson, T Simonson… - Journal of Applied …, 2017 - journals.physiology.org
We have developed a novel functional proton magnetic resonance imaging (MRI) technique
to measure regional ventilation-perfusion (V̇A/Q̇) ratio in the lung. We conducted a …

The gravitational distribution of ventilation-perfusion ratio is more uniform in prone than supine posture in the normal human lung

AC Henderson, RC Sá, RJ Theilmann… - Journal of applied …, 2013 - journals.physiology.org
The gravitational gradient of intrapleural pressure is suggested to be less in prone posture
than supine. Thus the gravitational distribution of ventilation is expected to be more uniform …

3He MRI-based assessment of posture-dependent regional ventilation gradients in rats

S Mansson, AJ Deninger… - Journal of Applied …, 2005 - journals.physiology.org
A recently developed method for quantitative assessment of regional lung ventilation was
employed for the study of posture-dependent ventilation differences in rats. The …

Advances in magnetic resonance imaging of lung physiology

SR Hopkins, DL Levin, K Emami… - Journal of applied …, 2007 - journals.physiology.org
This review presents an overview of some recent magnetic resonance imaging (MRI)
techniques for measuring aspects of local physiology in the lung. MRI is noninvasive …

Advances in functional and structural imaging of the human lung using proton MRI

GW Miller, JP Mugler III, RC Sá, TA Altes… - NMR in …, 2014 - Wiley Online Library
The field of proton lung MRI is advancing on a variety of fronts. In the realm of functional
imaging, it is now possible to use arterial spin labeling (ASL) and oxygen‐enhanced …

Lung ventilation volumetry with same‐breath acquisition of hyperpolarized gas and proton MRI

FC Horn, BA Tahir, NJ Stewart, GJ Collier… - NMR in …, 2014 - Wiley Online Library
The purpose of this work was to assess the reproducibility of percentage of ventilated lung
volume (PV) measured from hyperpolarized (HP) 3He and 1H anatomical images acquired …

Probing the regional distribution of pulmonary gas exchange through single-breath gas- and dissolved-phase 129Xe MR imaging

SS Kaushik, MS Freeman… - Journal of applied …, 2013 - journals.physiology.org
Although some central aspects of pulmonary function (ventilation and perfusion) are known
to be heterogeneous, the distribution of diffusive gas exchange remains poorly …

Influence of oxygen flow rate on signal and T1 changes in oxygen‐enhanced ventilation imaging

VM Mai, B Liu, W Li, J Polzin, S Kurucay… - Journal of Magnetic …, 2002 - Wiley Online Library
Purpose To investigate the optimal oxygen flow rate for oxygen‐enhanced MR ventilation
imaging. Materials and Methods Using a cardiac‐triggered nonselective inversion recovery …