The nEUROPt protocol is one of two new protocols developed within the European project
nEUROPt to characterize the performances of time-domain systems for optical imaging of …

Performance assessment of instruments devised for clinical applications is of key
importance for validation and quality assurance. Two new protocols were developed and …

A Time-Domain NIR Brain Imager Applied in Functional Stimulation Experiments Page 1 A
Time-Domain NIR Brain Imager Applied in Functional Stimulation Experiments H. Wabnitz …

We present a time-domain optical system for functional imaging of the adult head. We first
describe the instrument, which is based on a Ti: Sapphire pulsed laser (wavelength 750 …

Time domain (TD) diffuse optical measurement systems are being applied to neuroimaging,
where they can detect hemodynamics changes associated with cerebral activity. We show …

Significance: The optical properties of biological samples provide information about the
structural characteristics of the tissue and any changes arising from pathological conditions …

Optical brain imaging has seen 30 years of intense development, and has grown into a rich
and diverse field. In-vivo imaging using light provides unprecedented sensitivity to functional …

Significance: Time-domain functional near-infrared spectroscopy (TD-fNIRS) has been
considered as the gold standard of noninvasive optical brain imaging devices. However …

Understanding how the brain functions is one of the grand challenges in modern scientific
research. Similar to a computer, a functional brain is composed of hardware and software …

A novel approach to improve depth selectivity based on time-domain contrast functions is
presented. The method was tested with Monte Carlo simulations showing sensitivity to …