Urinary bladder smooth muscle engineered from adipose stem cells and a three dimensional synthetic composite
Human adipose stem cells were cultured in smooth muscle inductive media and seeded into
synthetic bladder composites to tissue engineer bladder smooth muscle. 85: 15 Poly-lactic …
synthetic bladder composites to tissue engineer bladder smooth muscle. 85: 15 Poly-lactic …
Phenotypic and functional characterization of in vivo tissue engineered smooth muscle from normal and pathological bladders
JY Lai, CY Yoon, JJ Yoo, T Wulf, A Atala - The Journal of urology, 2002 - auajournals.org
Purpose: The engineering of bladder tissue involves obtaining a biopsy from a host,
expanding the cells, seeding them onto a matrix and implanting the cell-matrix composite …
expanding the cells, seeding them onto a matrix and implanting the cell-matrix composite …
Regeneration of native-like neo-urinary tissue from nonbladder cell sources
J Basu, MJ Jayo, RM Ilagan, KI Guthrie… - … Engineering Part A, 2012 - liebertpub.com
Urinary pathology requiring urinary diversion, partial or full bladder replacement, is a
significant clinical problem affecting∼ 14,000 individuals annually in the United States …
significant clinical problem affecting∼ 14,000 individuals annually in the United States …
Bioengineered bladder patches constructed from multilayered adipose-derived stem cell sheets for bladder regeneration
Y Wang, S Zhou, R Yang, Q Zou, K Zhang, Q Tian… - Acta Biomaterialia, 2019 - Elsevier
Cell-seeded scaffolds are a common route of cell transplantation for bladder repair and
reconstruction. However, when cell suspensions are harvested, proteolytic enzymes often …
reconstruction. However, when cell suspensions are harvested, proteolytic enzymes often …
Bladder acellular matrix grafts seeded with adipose-derived stem cells and incubated intraperitoneally promote the regeneration of bladder smooth muscle and nerve …
Z Zhe, D Jun, Z Yang, X Mingxi, Z Ke… - Stem Cells and …, 2016 - liebertpub.com
The objective of this study was to investigate the feasibility of bladder acellular matrix grafts
(BAMGs) seeded with adipose-derived stem cells (ASCs) followed by intraperitoneal …
(BAMGs) seeded with adipose-derived stem cells (ASCs) followed by intraperitoneal …
Understanding the role of mesenchymal stem cells in urinary bladder regeneration—a preclinical study on a porcine model
M Pokrywczynska, A Jundzill, M Rasmus… - Stem cell research & …, 2018 - Springer
Background The tissue engineering of urinary bladder advances rapidly reflecting clinical
need for a new kind of therapeutic solution for patients requiring urinary bladder …
need for a new kind of therapeutic solution for patients requiring urinary bladder …
Engineering functional bladder tissues
M Horst, S Madduri, R Gobet, T Sulser… - Journal of tissue …, 2013 - Wiley Online Library
Purpose: End stage bladder disease can seriously affect patient quality of life and often
requires surgical reconstruction with bowel tissue, which is associated with numerous …
requires surgical reconstruction with bowel tissue, which is associated with numerous …
Biaxial mechanical properties of muscle-derived cell seeded small intestinal submucosa for bladder wall reconstitution
Bladder wall replacement remains a challenging problem for urological surgery due to
leakage, infection, stone formation, and extensive time needed for tissue regeneration. To …
leakage, infection, stone formation, and extensive time needed for tissue regeneration. To …
Urinary bladder smooth muscle regeneration utilizing bone marrow derived mesenchymal stem cell seeded elastomeric poly (1, 8-octanediol-co-citrate) based thin …
AK Sharma, PV Hota, DJ Matoka, NJ Fuller, D Jandali… - Biomaterials, 2010 - Elsevier
Bladder regeneration studies have yielded inconclusive results possibly due to the use of
unfavorable cells and primitive scaffold design. We hypothesized that human mesenchymal …
unfavorable cells and primitive scaffold design. We hypothesized that human mesenchymal …
Tissue engineering of human bladder
A Atala - British medical bulletin, 2011 - academic.oup.com
There are a number of conditions of the bladder that can lead to loss of function. Many of
these require reconstructive procedures. However, current techniques may lead to a number …
these require reconstructive procedures. However, current techniques may lead to a number …
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