Immunopotentiator-loaded polymeric microparticles as robust adjuvant to improve vaccine efficacy
Purpose Adjuvants are required to ensure the efficacy of subunit vaccines. Incorporating
molecular immunopotentiators within particles could overcome drawbacks of molecular …
molecular immunopotentiators within particles could overcome drawbacks of molecular …
Combination of immune stimulating adjuvants with poly (lactide-co-glycolide) microspheres enhances the immune response of vaccines
The development of vaccines that generate mixed humoral and cellular immune responses
is a challenge in vaccinology. Poly (lactide-co-glycolide) microspheres are vaccine …
is a challenge in vaccinology. Poly (lactide-co-glycolide) microspheres are vaccine …
Time course study of the antigen-specific immune response to a PLGA microparticle vaccine formulation
Q Wang, MT Tan, BP Keegan, MA Barry, MJ Heffernan - Biomaterials, 2014 - Elsevier
Microparticle-based vaccine delivery systems are known to promote enhanced immune
responses to protein antigens and can elicit TH 1-biased responses when used in …
responses to protein antigens and can elicit TH 1-biased responses when used in …
Adjuvanticity regulation by biodegradable polymeric nano/microparticle size
Polymeric nano/microparticles as vaccine adjuvants have been researched in experimental
and clinical studies. A more profound understanding of how the physicochemical properties …
and clinical studies. A more profound understanding of how the physicochemical properties …
Non-carrier nanoparticles adjuvant modular protein vaccine in a particle-dependent manner
A Seth, FK Ritchie, N Wibowo, LHL Lua… - PloS one, 2015 - journals.plos.org
Nanoparticles are increasingly used to adjuvant vaccine formulations due to their
biocompatibility, ease of manufacture and the opportunity to tailor their size, shape, and …
biocompatibility, ease of manufacture and the opportunity to tailor their size, shape, and …
[PDF][PDF] Navigating the landscape of adjuvants for subunit vaccines: Recent advances and future perspectives
FL Orosco, LM Espiritu - Int. J. Appl. Pharmaceut, 2024 - pdfs.semanticscholar.org
The development of effective subunit vaccines relies on the incorporation of adjuvants to
enhance immune responses and improve vaccine efficacy. This paper provides a …
enhance immune responses and improve vaccine efficacy. This paper provides a …
Comparative study of acetalated-dextran microparticle fabrication methods for a clinically translatable subunit-based influenza vaccine
The most common influenza vaccines are inactivated viruses produced in chicken eggs,
which is a time-consuming production method with variable efficacy due to mismatches of …
which is a time-consuming production method with variable efficacy due to mismatches of …
Influence of particle size, an elongated particle geometry, and adjuvants on dendritic cell activation
Modern subunit vaccines have many benefits compared to live vaccines such as convenient
and competitive large scale production, better reproducibility and safety. However, the poor …
and competitive large scale production, better reproducibility and safety. However, the poor …
Polycation-decorated PLA microspheres induce robust immune responses via commonly used parenteral administration routes
Recombinant viral subunit-based vaccines have gained increasing attention due to their
enhanced safety over the classic live-attenuated or inactivated vaccines. The low …
enhanced safety over the classic live-attenuated or inactivated vaccines. The low …
Rational design of polymer‐based particulate vaccine adjuvants
J Huete‐Carrasco, RI Lynch, RW Ward… - European Journal of …, 2024 - Wiley Online Library
Vaccination is considered one of the major milestones in modern medicine, facilitating the
control and eradication of life‐threatening infectious diseases. Vaccine adjuvants are a key …
control and eradication of life‐threatening infectious diseases. Vaccine adjuvants are a key …